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View trial details
Overview
Official protocol title:
A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED, MULTICENTER STUDY ASSESSING OLPASIRAN USE TO PREVENT FIRST MAJOR CARDIOVASCULAR EVENTS IN PARTICIPANTS WITH ELEVATED LIPOPROTEIN(A)
Intervention/treatment:
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
OLPASIRAN (AMG 890)
Medical condition:
The disease or condition that's being studied in the clinical trial.
Protocol code:
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
20230222
Control number:
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
297089
Status:
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site.
• Recruiting - Participants are currently being recruited.
• Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled.
• On hold - The clinical trial has been temporarily stopped, but it may start again.
• Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again.
• Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor.
• No match, ongoing - Please contact sponsor for status information.
• Other - Please contact sponsor for status information.
Recruiting
Approved:
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
May 13, 2025
Trial phase:
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
Phase 3
For more information:
ClinicalTrials.gov -
NCT07136012
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Accepts healthy volunteers:
No
Locations
Alberta
Centricity Research Calgary
Calgary, Alberta, T2H 2G4
RECRUITING
Edmonton Cardiology Consultants
Edmonton, Alberta, T5H 4B9
RECRUITING
British Columbia
ARC Biosystems Incorporated
Vancouver, British Columbia, V6Z 1Y6
RECRUITING
Discovery Clinical Services Ltd
Victoria, British Columbia, V8T 5G4
RECRUITING
Fraser Clinical Trials
New Westminster, British Columbia, V3L 3W4
RECRUITING
SMH Cardiology Clinical Trials Incorporated
Surrey, British Columbia, V3V 0C6
RECRUITING
Victoria Heart Institute Foundation
Victoria, British Columbia, V8R 1B2
RECRUITING
Ontario
Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6
RECRUITING
Centricity Research Brampton
Brampton, Ontario, L6S 0C6
RECRUITING
Circulate Cardiac & Vascular Centre
Burlington, Ontario, L7M 1K9
RECRUITING
Elevate Clinical Research KMH Missisauga
Mississauga, Ontario, L5K 2L3
RECRUITING
Hamilton Health Sciences Hamilton General Hospital
Hamilton, Ontario, L8L 2X2
RECRUITING
Heart Health Institute Research Incorporated
Scarborough Village, Ontario, M1B 4Z8
RECRUITING
North York Diagnostic and Cardiac Centre
North York, Ontario, M6B 3H7
RECRUITING
Oakville Cardiovascular Research
Oakville, Ontario, L6K 3W7
RECRUITING
Partners in Advanced Cardiac Evaluation
Newmarket, Ontario, L3Y 8C3
RECRUITING
Premier Clinical Trial Network
Hamilton, Ontario, L8L 5G4
COMPLETED
St Josephs Hospital
London, Ontario, N6A 4V2
RECRUITING
Womens College Hospital
Toronto, Ontario, M5S 1B2
RECRUITING
Quebec
Centre de Recherche du Centre Hospitalier de l Universite de Montreal
Montreal, Quebec, H2W 1T8
RECRUITING
CIUSSS de l Estrie CHUS Hopital Fleurimont
Sherbrooke, Quebec, J1H 5N4
RECRUITING
Ecogene-21
Chicoutimi, Quebec, G7H 7K9
RECRUITING
Institut de recherches cliniques de Montreal
Montreal, Quebec, H2W 1R7
RECRUITING
Montreal Heart Institute
Montreal, Quebec, H1T 1C8
RECRUITING
Research Institute of McGill University Health Center - Glen Site
Montreal, Quebec, H4A 3J1
RECRUITING