OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Last updated:
2026-08-15
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View trial details

Overview

Official protocol title:

A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED, MULTICENTER STUDY ASSESSING OLPASIRAN USE TO PREVENT FIRST MAJOR CARDIOVASCULAR EVENTS IN PARTICIPANTS WITH ELEVATED LIPOPROTEIN(A)

Intervention/treatment:
OLPASIRAN (AMG 890)
Medical condition:
CARDIOVASCULAR DISEASE
Protocol code:
20230222
Control number:
297089
Status:
Recruiting
Approved:
May 13, 2025
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT07136012
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
50 Years to 105 Years
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Amgen Call Center
Role
CONTACT
Phone:
866-572-6436
Sponsor
AMGEN CANADA INC

Locations

Alberta

Centricity Research Calgary
Calgary, Alberta, T2H 2G4
RECRUITING
Edmonton Cardiology Consultants
Edmonton, Alberta, T5H 4B9
RECRUITING

British Columbia

ARC Biosystems Incorporated
Vancouver, British Columbia, V6Z 1Y6
RECRUITING
Discovery Clinical Services Ltd
Victoria, British Columbia, V8T 5G4
RECRUITING
Fraser Clinical Trials
New Westminster, British Columbia, V3L 3W4
RECRUITING
SMH Cardiology Clinical Trials Incorporated
Surrey, British Columbia, V3V 0C6
RECRUITING
Victoria Heart Institute Foundation
Victoria, British Columbia, V8R 1B2
RECRUITING

Ontario

Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6
RECRUITING
Centricity Research Brampton
Brampton, Ontario, L6S 0C6
RECRUITING
Circulate Cardiac & Vascular Centre
Burlington, Ontario, L7M 1K9
RECRUITING
Elevate Clinical Research KMH Missisauga
Mississauga, Ontario, L5K 2L3
RECRUITING
Hamilton Health Sciences Hamilton General Hospital
Hamilton, Ontario, L8L 2X2
RECRUITING
Heart Health Institute Research Incorporated
Scarborough Village, Ontario, M1B 4Z8
RECRUITING
North York Diagnostic and Cardiac Centre
North York, Ontario, M6B 3H7
RECRUITING
Oakville Cardiovascular Research
Oakville, Ontario, L6K 3W7
RECRUITING
Partners in Advanced Cardiac Evaluation
Newmarket, Ontario, L3Y 8C3
RECRUITING
Premier Clinical Trial Network
Hamilton, Ontario, L8L 5G4
COMPLETED
St Josephs Hospital
London, Ontario, N6A 4V2
RECRUITING
Womens College Hospital
Toronto, Ontario, M5S 1B2
RECRUITING

Quebec

Centre de Recherche du Centre Hospitalier de l Universite de Montreal
Montreal, Quebec, H2W 1T8
RECRUITING
CIUSSS de l Estrie CHUS Hopital Fleurimont
Sherbrooke, Quebec, J1H 5N4
RECRUITING
Ecogene-21
Chicoutimi, Quebec, G7H 7K9
RECRUITING
Institut de recherches cliniques de Montreal
Montreal, Quebec, H2W 1R7
RECRUITING
Montreal Heart Institute
Montreal, Quebec, H1T 1C8
RECRUITING
Research Institute of McGill University Health Center - Glen Site
Montreal, Quebec, H4A 3J1
RECRUITING
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