A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Last updated:
2026-08-15
Language and content disclaimer

The content and search results on this site are collected from or provided by third parties. As such some of the information may only be available in the language originally submitted by the sponsor of the trial. Learn more about the information on the search portal.

Linking to Non-Government of Canada Websites

Links to websites not under the control of the Government of Canada, including those to our social media accounts, and to clinical trial records in international registries are provided solely for the convenience of our website visitors. We are not responsible for the accuracy, currency or reliability of the content of such websites. The Government of Canada does not offer any guarantee in that regard and is not responsible for the information found through these links, nor does it endorse the sites and their content.

Visitors should also be aware that information offered by non-Government of Canada sites to which this website links is not subject to the Privacy Act or the Official Languages Act and may not be accessible to persons with disabilities. The information offered may be available only in the language(s) used by the sites in question. With respect to privacy, visitors should research the privacy policies of these non-government websites before providing personal information.

View trial details

Overview

Official protocol title:

EASI-HF - A PHASE III DOUBLE-BLIND, RANDOMISED, PARALLEL-GROUP SUPERIORITY TRIAL TO EVALUATE EFFICACY AND SAFETY OF THE COMBINED USE OF ORAL BI 690517 AND EMPAGLIFLOZIN COMPARED WITH PLACEBO AND EMPAGLIFLOZIN IN PARTICIPANTS WITH SYMPTOMATIC HEART FAILURE (HF: NYHA II-IV) AND LEFT VENTRICULAR EJECTION FRACTION (LVEF) >40%

Intervention/treatment:
VICADROSTAT (BI 690517) / EMPAGLIFLOZIN
Medical condition:
HEART FAILURE
Protocol code:
1378-0020
Control number:
288109
Status:
Recruiting
Approved:
July 24, 2024
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT06424288
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
1-800-243-0127
Sponsor
BOEHRINGER INGELHEIM INTERNATIONAL GMBH

Locations

Ontario

Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
CardioQuest Research Centre
Sarnia, Ontario, N7T 4P5
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
CardioVasc HR Inc.
Saint-Jean-sur-Richelieu, Ontario, J3A 1J2
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Centre Hospitalier de l'Universite de Montreal (CHUM)
Montreal, Ontario, H2X 0C1
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Clinical Research Solutions Inc. (Kitchener)
Kitchener, Ontario, N2H5Z8
NOT_YET_RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Curnew Medicine Professional Corporation
Hamilton, Ontario, L8L 0A9
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Health Sciences North
Greater Sudbury, Ontario, P3E 5J1
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
James Cha, MD
Oshawa, Ontario, L1J 2K1
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
KMH Cardiology Centers (Hamilton)
Stoney Creek, Ontario, L8J 3W2
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
KMH Cardiology Centres (Mississauga)
Mississauga, Ontario, L5K 2L3
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Montreal General Hospital - McGill University Health Centre
Montreal, Ontario, H3G 1A4
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Oakville Trafalgar Memorial Hospital
Oakville, Ontario, L6M 0L8
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Royal Alexandra Hospital (Edmonton)
Edmonton, Ontario, T5H 3V9
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346

Quebec

Diex Recherche (Trois-Rivieres)
Trois-Rivières, Quebec, G9A 4P3
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Jewish General Hospital
Montreal, Quebec, H3T 1E2
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
ViaCar Recherches Cliniques Inc. (Greenfield Park)
Greenfield Park, Quebec, J4V 2G8
RECRUITING
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Did you find what you were looking for?