A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Last updated:
2026-07-18
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View trial details

Overview

Official protocol title:

A PHASE 3, MULTICENTER, DOUBLE-BLIND MAINTENANCE STUDY TO ASSESS LONGTERM SAFETY, TOLERABILITY, AND EFFICACY OF ROCATINLIMAB IN ADULT AND ADOLESCENT SUBJECTS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS (AD) (ROCKET-ASCEND)

Intervention/treatment:
ROCATINLIMAB (AMG 451)
Medical condition:
ATOPIC DERMATITIS
Protocol code:
20210146
Control number:
273869
Status:
Closed
Approved:
May 12, 2023
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT05882877
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
12 Years to 100 Years
Accepts healthy volunteers: No

Contacts and locations

Contact
Sponsor
AMGEN CANADA INC

Locations

Alberta

Alberta Derma Surgery Centre
Edmonton, Alberta, T6G 1C3
Beacon Dermatology
Calgary, Alberta, T3E 0B2
Dermatology Research Institute Incorporated
Calgary, Alberta, T2J 7E1
Laser Rejuvenation Clinics Edmonton D T Incorporated
Edmonton, Alberta, T5J 3S9
Rejuvenation Dermatology Laser Calgary North
Calgary, Alberta, T3K 6B8
Skin Physicians Dermatology
Edmonton, Alberta, T6W 4V4
Stratica Dermatology
Edmonton, Alberta, T5K 1X3
Vida Clinical Research
Edmonton, Alberta, T6H 4J8

British Columbia

Doctor Chih-Ho Hong Medical Incorporated
Surrey, British Columbia, V3R 6A7
Enverus Medical Research
Surrey, British Columbia, V3V 0C6
Interior Dermatology Centre
Kelowna, British Columbia, V1W 4V5

Manitoba

Winnipeg Clinic Dermatology Research
Winnipeg, Manitoba, R3C 0N2
Wiseman Dermatology Research Incorporated
Winnipeg, Manitoba, R3M 3Z4

Newfoundland and Labrador

Karma Clinical Trials
St. John's, Newfoundland and Labrador, A1A 4Y3

Ontario

Allergy Research Canada Incorporated
Niagara Falls, Ontario, L2H 1H5
Alliance Clinical Trials
Waterloo, Ontario, N2J 1C4
Canadian Dermatology Centre
North York, Ontario, M3B 0A7
CCA Medical Research Corp
Ajax, Ontario, L1S 7K8
Centricity Research London Victoria
London, Ontario, N6A 2C2
Dermatology Ottawa Research Centre
Ottawa, Ontario, K2C 3N2
DermEdge Research Incorporated
Mississauga, Ontario, L4Y 4C5
Evidence Based Medical Educator Inc
Toronto, Ontario, M5G 1E2
FACET Dermatology
Toronto, Ontario, M4E 1R7
Guelph Dermatology Research
Guelph, Ontario, N1L 0B7
Halton Pediatric Allergy
Burlington, Ontario, L7L 6W6
JRB Research Incorporated
Ottawa, Ontario, K1K 4L2
Kingsway Clinical Research
Etobicoke, Ontario, M8X 1Y9
LEADER Research
Hamilton, Ontario, L8L 3C3
Lynderm Research Inc
Markham, Ontario, L3P 1X3
North Bay Dermatology Centre
North Bay, Ontario, P1B 3Z7
North York Research Incorporated
Toronto, Ontario, M2N 3A6
Oak Ridges Aesthetics Centre
Richmond Hill, Ontario, L4E 4L6
Research Toronto
Toronto, Ontario, M4W 2N4
Ryan Clinical Research Incorporated
Newmarket, Ontario, L3Y 5G8
SimcoDerm Medical and Surgical Dermatology Centre
Barrie, Ontario, L4M 7G1
SKiN Centre for Dermatology
Peterborough, Ontario, K9J 5K2
SKiN Health
Coburg, Ontario, K9A 0Z4
The Centre for Clinical Trials Inc
Oakville, Ontario, L6J 7W5
The Centre for Dermatology
Richmond Hill, Ontario, L4B 1A5
Toronto Research Centre Inc
Toronto, Ontario, M3H 5Y8
Triple A Lab
Hamilton, Ontario, L8S 1G5
XLR8 Medical Research, Incorporated
Windsor, Ontario, N8T 1E6
York Dermatology Clinic and Research Centre
Richmond Hill, Ontario, L4B 1L1

Quebec

Centre de Recherche Dermatologique du Quebec Metropolitain
Québec, Quebec, G1V 4X7
Clinique de Dermatologie Rosemont
Montreal, Quebec, H1Y 3L1
Clinique Medicale Saint Louis
Québec, Quebec, G1W 4R4
Innovaderm Research Inc
Montreal, Quebec, H2X 2V1
Recherche Clinique Sigma Incorporated
Québec, Quebec, G1G 3Y8

Saskatchewan

Saskatoon Dermatology Centre
Saskatoon, Saskatchewan, S7T 0G3
Skinsense Medical Research
Saskatoon, Saskatchewan, S7K 2C1
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