A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Last updated:
2026-08-15
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View trial details

Overview

Official protocol title:

A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY TO EVALUATE EFFICACY AND SAFETY OF UPADACITINIB IN ADULT AND ADOLESCENT SUBJECTS WITH MODERATE TO SEVERE HIDRADENITIS SUPPURATIVA WHO HAVE FAILED ANTI-TNF THERAPY

Intervention/treatment:
UPADACITINIB (ABT-494)
Medical condition:
HIDRADENITIS SUPPURATIVA
Protocol code:
M23-698
Control number:
273382
Status:
Active, not recruiting
Approved:
May 30, 2023
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT05889182
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
12 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
ABBVIE CALL CENTER
Role
CONTACT
Phone:
844-663-3742
Sponsor
ABBVIE CORPORATION

Locations

Alberta

Alberta Dermasurgery Centre /ID# 275945
Edmonton, Alberta, T6G 1C3
Active, not recruiting
Beacon Dermatology /ID# 254564
Calgary, Alberta, T3A 2N1
Active, not recruiting
Care Clinic - Red Deer - Taylor Drive /ID# 276063
Red Deer, Alberta, T4P 1K4
Active, not recruiting
Dermatology Research Institute - Blackfoot Trail /ID# 261413
Calgary, Alberta, T2J 7E1
Active, not recruiting
Rejuvenation Dermatology - Edmonton Downtown /ID# 254715
Edmonton, Alberta, T5J 3S9
Active, not recruiting

British Columbia

Dr. Chih-ho Hong Medical Inc. /ID# 254378
Surrey, British Columbia, V3R 6A7
Active, not recruiting
Enverus Medical Research /ID# 254380
Surrey, British Columbia, V3V 0C6
COMPLETED

Manitoba

Wiseman Dermatology Research /ID# 254117
Winnipeg, Manitoba, R3M 3Z4
Active, not recruiting

Newfoundland and Labrador

Karma Clinical Trials /ID# 254120
St. John's, Newfoundland and Labrador, A1A 4Y3
Active, not recruiting

Ontario

Derm Care Clinic /ID# 276065
Mississauga, Ontario, L4W 0C2
Active, not recruiting
DermEffects /ID# 254116
London, Ontario, N6H 5L5
Active, not recruiting
Diex Recherche Quebec Inc. /ID# 254381
Québec, Ontario, G1V 4T3
Active, not recruiting
LEADER Research /ID# 254379
Hamilton, Ontario, L8L 3C3
Active, not recruiting
Lynderm Research Inc /ID# 254713
Markham, Ontario, L3P 1X2
Active, not recruiting
Research Toronto /ID# 255273
Toronto, Ontario, M4W 2N4
Active, not recruiting
Ryan Clinical Research Inc /ID# 254714
Newmarket, Ontario, L3Y 5G8
Active, not recruiting
York Dermatology Clinic and Research Centre /ID# 254115
Richmond Hill, Ontario, L4C 9M7
Active, not recruiting

Quebec

CHU Sainte-Justine /ID# 254118
Montreal, Quebec, H3T 1C5
Active, not recruiting
Dre Angelique Gagne-Henley M.D. inc. /ID# 255632
Saint-Jérôme, Quebec, J7Z 7E2
Active, not recruiting

Saskatchewan

SkinSense Dermatology /ID# 254119
Saskatoon, Saskatchewan, S7K 0H6
Active, not recruiting
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