A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Last updated:
2026-08-22
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View trial details

Overview

Official protocol title:

EFFICACY AND SAFETY OF NNC0487-0111 COMPARED TO PLACEBO ON MORBIDITY AND MORTALITY IN PEOPLE WITH HEART FAILURE WITH PRESERVED OR MILDLY REDUCED EJECTION FRACTION AND OBESITY (HF-POLARIS)

Intervention/treatment:
NNC0487-0111
Medical condition:
HEART FAILURE
Protocol code:
NN9490-8266
Control number:
305813
Status:
Recruiting
Approved:
March 19, 2026
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT07567001
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Novo Nordisk
Role
CONTACT
Phone:
(+1) 866-867-7178
Sponsor
NOVO NORDISK CANADA INC

Locations

CHU de Quebec-Uni Laval-Hotel
Québec, G1R2J6
RECRUITING
IUCPQ - Universite Laval
Québec, G1V 4G5
RECRUITING

Alberta

University of Calgary
Calgary, Alberta, T2N 4Z6
RECRUITING

British Columbia

St Pauls Hospital
Vancouver, British Columbia, V6Z1Y6
NOT_YET_RECRUITING

Manitoba

St. Boniface Hospital
Winnipeg, Manitoba, R2H 2A6
NOT_YET_RECRUITING

New Brunswick

G.A. Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7
RECRUITING

Nova Scotia

Nova Scotia Health
Halifax, Nova Scotia, B3H 3A7
NOT_YET_RECRUITING

Ontario

Cardiac Institute for Research at Queen's - CIRQ
Kingston, Ontario, K7L 2V7
NOT_YET_RECRUITING
Cardio Health Clinical Trials
Hamilton, Ontario, L8W 3K5
RECRUITING
Circulate Cardiac and Vascular Centre
Burlington, Ontario, L8P 2N4
NOT_YET_RECRUITING
Corcare Cardiovascular Research
Scarborough Village, Ontario, M1B 5N1
NOT_YET_RECRUITING
CPS Research
Waterloo, Ontario, N2T 0C1
RECRUITING
Curnew Medicine Professional Corporation
Hamilton, Ontario, L8L 0A9
RECRUITING
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
RECRUITING
Halton Healthcare
Oakville, Ontario, L6M 0L8
NOT_YET_RECRUITING
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2
NOT_YET_RECRUITING
Med Trust Research, Inc.
Courtice, Ontario, L1E 2J5
NOT_YET_RECRUITING
North York Diagn & Cardiac Ctr
North York, Ontario, M6B 3H7
RECRUITING
St. Joseph's Heath Centre
Toronto, Ontario, M6N1B5
NOT_YET_RECRUITING
Winchester Dist Memorial Hosp
Winchester, Ontario, K0C 2K0
RECRUITING
Women's College Hospital
Toronto, Ontario, M5S 1B1
NOT_YET_RECRUITING

Quebec

C.I.C. Joliette
Saint-Charles-Borromée, Quebec, J6E 2B4
NOT_YET_RECRUITING
CHUM-Hosp de Univ Montreal
Montreal, Quebec, H2X 0C1
NOT_YET_RECRUITING
CISSS BAS ST-LAURENT, HOPITAL regional DE RIMOUSKI
Rimouski, Quebec, G5L5T1
NOT_YET_RECRUITING
CIUSSS du Saguenay-Lac-St-Jean
Chicoutimi, Quebec, G7H 5H6
RECRUITING
Diex Recherche Sherbrooke
Sherbrooke, Quebec, J1E 0N8
RECRUITING
Diex Recherche Trois-Rivieres
Trois-Rivières, Quebec, G9A 4P3
RECRUITING
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