A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

Last updated:
2026-07-18
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View trial details

Overview

Official protocol title:

A PHASE 3 STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF ORFORGLIPRON ONCE DAILY IN PARTICIPANTS WHO HAVE OBESITY OR OVERWEIGHT AND OSTEOARTHRITIS OF THE KNEE: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PARALLEL-ARM, PLACEBO-CONTROLLED TRIAL (ATTAIN-OA PAIN)

Intervention/treatment:
ORFORGLIPRON (LY3502970)
Medical condition:
OSTEOARTHRITIS OF THE KNEE
Protocol code:
J2A-MC-GZPT
Control number:
300788
Status:
Recruiting
Approved:
September 12, 2025
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT07153471
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
Role
CONTACT
Phone:
1-317-615-4559
Name
Physicians interested in becoming principal investigators please contact
Role
CONTACT
Sponsor
ELI LILLY CANADA INC

Locations

Aggarwal and Associates Limited
Brampton, L6T 0G1
RECRUITING
Role
CONTACT
Phone:
9054589033
Name
Naresh Aggarwal
Role
PRINCIPAL_INVESTIGATOR
Alpha Recherche Clinique
Québec, G2J 0C4
RECRUITING
Name
Nancy Labrecque
Role
PRINCIPAL_INVESTIGATOR
ALPHA Recherche Clinique
Québec, G3K 2P8
RECRUITING
Role
CONTACT
Phone:
418-847-1112
Name
Xavier Mignault
Role
PRINCIPAL_INVESTIGATOR
Bluewater Clinical Research Group Inc.
Sarnia, N7T 4X3
RECRUITING
Role
CONTACT
Phone:
1 (519) 344-6612
Name
John O'Mahony
Role
PRINCIPAL_INVESTIGATOR
Diex Recherche Inc. Division Joliette
Joliette, J6E 6A9
RECRUITING
Role
CONTACT
Phone:
450-755-2525
Name
Jean-Sebastien Paquette
Role
PRINCIPAL_INVESTIGATOR
Dr. M.B. Jones Inc.
Victoria, V8V 4A1
NOT_YET_RECRUITING
Role
CONTACT
Phone:
2503833311
Name
Michael Jones
Role
PRINCIPAL_INVESTIGATOR
G.R.M.O. (Groupe de recherche en maladies osseuses) Inc.
Québec, G1V 4K5
RECRUITING
Role
CONTACT
Phone:
418 650-2661
Name
Louis Bessette
Role
PRINCIPAL_INVESTIGATOR
Winterberry Research Inc.
Stoney Creek, L8J 0B6
RECRUITING
Role
CONTACT
Phone:
365-366-6267
Name
Steven Zizzo
Role
PRINCIPAL_INVESTIGATOR
Your Research Network
Niagara Falls, L2H 1H5
RECRUITING
Name
Mondeesh Sidhu
Role
PRINCIPAL_INVESTIGATOR
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