Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

Last updated:
2026-08-15
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View trial details

Overview

Official protocol title:

A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFECT OF MUVALAPLIN ON THE REDUCTION OF MAJOR ADVERSE CARDIOVASCULAR EVENTS IN ADULTS WITH ELEVATED LIPOPROTEIN(A) WHO HAVE HAD A PRIOR ATHEROSCLEROTIC CARDIOVASCULAR EVENT OR ARE AT RISK FOR A FIRST ATHEROSCLEROTIC CARDIOVASCULAR EVENT ¿ MOVE-LP(A)

Intervention/treatment:
MUVALAPLIN (LY3473329)
Medical condition:
CARDIOVASCULAR DISEASE
Protocol code:
J2O-MC-EKBG
Control number:
299260
Status:
Recruiting
Approved:
July 22, 2025
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT07157774
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
Role
CONTACT
Phone:
1-317-615-4559
Name
Physicians interested in becoming principal investigators please contact
Role
CONTACT
Sponsor
ELI LILLY CANADA INC

Locations

Bluewater Clinical Research Group Inc.
Sarnia, N7T 4X3
RECRUITING
Role
CONTACT
Phone:
1 (519) 344-6612
Name
John O'Mahony
Role
PRINCIPAL_INVESTIGATOR
Clinical Research Solutions - Kitchener
Waterloo, N2T 0C1
RECRUITING
Role
CONTACT
Phone:
519 743 2573
Name
Shivinder Jolly
Role
PRINCIPAL_INVESTIGATOR
Diex Recherche Inc. Division Joliette
Joliette, J6E 6A9
NOT_YET_RECRUITING
Name
Genevieve Mathieu
Role
CONTACT
Phone:
579-841-0571
Name
Laurence Laplante
Role
PRINCIPAL_INVESTIGATOR
Diex Recherche Inc. Division Trois-Rivieres
Trois-Rivières, G9A 4P3
RECRUITING
Role
CONTACT
Phone:
819-801-9797
Name
Ying Sia
Role
PRINCIPAL_INVESTIGATOR
Discovery Clinical Services
Victoria, V8T 5G4
RECRUITING
Role
CONTACT
Phone:
250-889-2639
Name
Gordon Hoag
Role
PRINCIPAL_INVESTIGATOR
Ecogene-21
Chicoutimi, G7H 7K9
RECRUITING
Role
CONTACT
Phone:
418-545-1252
Name
Daniel Gaudet
Role
PRINCIPAL_INVESTIGATOR
Fadia El Boreky Medicine
Waterloo, N2J 1C4
RECRUITING
Role
CONTACT
Phone:
519-569-7592
Name
Fadia El Boreky
Role
PRINCIPAL_INVESTIGATOR
G A Research Associates
Moncton, E1G 1A7
RECRUITING
Name
Jean-Claude Tardif
Role
CONTACT
Phone:
506-852-9865
Name
Jocelyn Cormier
Role
PRINCIPAL_INVESTIGATOR
Institut de Cardiologie de Montreal
Montreal, H1T 1C8
RECRUITING
Name
Jean-Claude Tardif
Role
PRINCIPAL_INVESTIGATOR
Phone:
4167830000
IUCPQ
Québec, G1V 4G5
RECRUITING
Role
CONTACT
Phone:
4186568711
Name
Jean-Pierre Déry
Role
PRINCIPAL_INVESTIGATOR
KMH Cardiology Centres - Stoney Creek
Stoney Creek, L8J 3W2
RECRUITING
Name
Beth Abramson
Role
CONTACT
Phone:
905 855 1860
Name
Fatima Merali
Role
PRINCIPAL_INVESTIGATOR
North York Diagnostic and Cardiac Centre
North York, M6B 3H7
RECRUITING
Role
CONTACT
Phone:
4167830000
Name
Subodh Verma
Role
PRINCIPAL_INVESTIGATOR
Riverside Cardiology and Diagnostic Imaging
Etobicoke, M8Z 4E4
RECRUITING
Role
CONTACT
Phone:
4167661162
Name
Peter Mitoff
Role
PRINCIPAL_INVESTIGATOR
Unity Health Toronto, St. Michael's Hospital
Toronto, M5B 1W8
RECRUITING
Name
Beth Abramson
Role
PRINCIPAL_INVESTIGATOR
Phone:
4167661162
Viacar Recherche Clinique
Longueuil, J4H 4B9
RECRUITING
Name
Genevieve Mathieu
Role
PRINCIPAL_INVESTIGATOR
Phone:
506-852-9865
Victoria Heart Institute Foundation
Victoria, V8R 1B2
RECRUITING
Role
CONTACT
Phone:
250-595-1884
Name
Christopher Franco
Role
PRINCIPAL_INVESTIGATOR
Winterberry Research Inc.
Hamilton, L8J 0B6
RECRUITING
Role
CONTACT
Phone:
365-366-6267
Name
Steven Zizzo
Role
PRINCIPAL_INVESTIGATOR
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