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View trial details
Overview
Official protocol title:
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE
THE IMPACT OF MARIDEBART CAFRAGLUTIDE ON CARDIOVASCULAR OUTCOMES IN
PARTICIPANTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE AND OVERWEIGHT OR
OBESITY (MARITIME-CV)
Intervention/treatment:
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
MARIDEBART CAFRAGLUTIDE (AMG 133)
Medical condition:
The disease or condition that's being studied in the clinical trial.
Protocol code:
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
20220196
Control number:
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
298511
Status:
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site.
• Recruiting - Participants are currently being recruited.
• Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled.
• On hold - The clinical trial has been temporarily stopped, but it may start again.
• Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again.
• Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor.
• No match, ongoing - Please contact sponsor for status information.
• Other - Please contact sponsor for status information.
Recruiting
Approved:
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
June 26, 2025
Trial phase:
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
Phase 3
For more information:
ClinicalTrials.gov -
NCT07037433
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Accepts healthy volunteers:
No
Locations
Alberta
Janek Senaratne Professional Medical Corporation
Edmonton, Alberta, T6K 4C1
Recruiting
British Columbia
Discovery Clinical Services Ltd
Victoria, British Columbia, V8T 5G4
Recruiting
Vancouver General Hospital, Gordon and Leslie Diamond Health Care Centre
Vancouver, British Columbia, V5Z 1M9
Recruiting
New Brunswick
G A Research Associates Limited
Moncton, New Brunswick, E1G 1A7
Recruiting
Ontario
Aggarwal and Associates Ltd
Brampton, Ontario, L6T 0G1
Recruiting
Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6
Recruiting
Centricity Research Brampton
Brampton, Ontario, L6S 0C6
Recruiting
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
Recruiting
Heart Health Institute Research Incorporated
Scarborough Village, Ontario, M1B 4Z8
Recruiting
KMH Cardiology Centres Incorporated Hamilton
Stoney Creek, Ontario, L8J 3W2
Recruiting
North York Diagnostic and Cardiac Centre
North York, Ontario, M6B 3H7
Recruiting
Quebec
Centre de Recherche du Centre Hospitalier de l Universite de Montreal
Montreal, Quebec, H2X 0C1
Recruiting
Centre intégré de santé et service sociaux de Lanaudière
Saint-Charles-Borromee, Quebec, J6E 6J2
Recruiting
Ecogene-21
Chicoutimi, Quebec, G7H 7K9
Recruiting
Institut Universitaire de cardiologie et de pneumologie de Quebec
Quebec, Quebec, G1V 4G5
Recruiting
Montreal Heart Institute
Montreal, Quebec, H1T 1C8
Recruiting
Research Institute of McGill University Health Center - Glen Site
Montreal, Quebec, H4A 3J1
TERMINATED