EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Last updated:
2026-10-03
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View trial details

Overview

Official protocol title:

A PHASE III DOUBLE-BLIND, RANDOMISED, PARALLEL-GROUP SUPERIORITY TRIAL TO EVALUATE EFFICACY AND SAFETY OF THE COMBINED USE OF ORAL VICADROSTAT (BI 690517) AND EMPAGLIFLOZIN COMPARED WITH PLACEBO AND EMPAGLIFLOZIN IN PARTICIPANTS WITH TYPE 2 DIABETES, HYPERTENSION AND ESTABLISHED CARDIOVASCULAR DISEASE. (EASI¿-PROTKT)

Intervention/treatment:
VICADROSTAT (BI 690517) / EMPAGLIFLOZIN (BI 10773)
Medical condition:
CARDIOVASCULAR DISEASE
Protocol code:
1378-0041
Control number:
298020
Status:
Recruiting
Approved:
June 13, 2025
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT07064473
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
1-800-243-0127
Sponsor
BOEHRINGER INGELHEIM INTERNATIONAL GMBH

Locations

Alberta

CaRe Clinic (Calgary)
Calgary, Alberta, T2N 4L7
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
CARe Clinic (Red Deer)
Red Deer, Alberta, T4P 1K4
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Diex Recherche (Quebec)
Quebec, Alberta, G1V 4T3
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346

British Columbia

Fraser Clinical Trials
New Westminster, British Columbia, V3L 3W4
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Medical Arts Research (Kelowna)
Kelowna, British Columbia, V1Y 4N7
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Medical Arts Research (North Vancouver)
Vancouver, British Columbia, V7P 2T4
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Medical Arts Research (Penticton)
Penticton, British Columbia, V2A 5L5
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
SMH Cardiology Clinical Trials Inc.
Surrey, British Columbia, V3V 0C6
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346

New Brunswick

GA Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346

Nova Scotia

QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 2Y9
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346

Ontario

CardioQuest Research Centre
Sarnia, Ontario, N7T 4P5
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Centre for Studies in Family Medicine, Western University (LHRI)
London, Ontario, N6G 2M1
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Heart Health Institute (Scarborough)
Scarborough Village, Ontario, M1B 4Z8
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
James Cha, MD
Oshawa, Ontario, L1J 2K1
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
KMH Cardiology Centres (Hamilton)
Stoney Creek, Ontario, L8J 3W2
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
KMH Cardiology Centres (Mississauga)
Mississauga, Ontario, L5K 2L3
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Medical Trust Clinics
Courtice, Ontario, L1E 2J5
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
PACE (Partners in Advanced Cardiac Evaluation)
Newmarket, Ontario, L3Y 2P6
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Saul Vizel Medicine Professional Corporation
Cambridge, Ontario, N1R 7R1
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
St. Michael's Hospital
Toronto, Ontario, M5B 1W8
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Stouffville Medical Research Institute Inc.
Stouffville, Ontario, L4A 1H2
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
University of Ottawa Heart Institute
Ottawa, Ontario, K1Y 4W7
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Women's College Hospital
Toronto, Ontario, M5S 1B2
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346

Quebec

Centre de Medecine Metabolique de Lanaudiere
Terrebonne, Quebec, J6X 4P7
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Diex Recherche (Joliette)
Joliette, Quebec, J6E 6A9
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Diex Recherche (Sherbrooke Est)
Sherbrooke, Quebec, J1E 0N8
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Diex Recherche (Trois-Rivieres)
Trois Rivieres, Quebec, G9A 4P3
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Ecogene-21
Chicoutimi, Quebec, G7H 7K9
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
Endocrinologie Oasis Inc
Montreal, Quebec, H4J 1E3
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
McGill University Health Centre (MUHC)
Montreal, Quebec, H4A 3J1
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
THEO Medical - Concorde (Laval)
Laval, Quebec, H7G 2E6
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
ViaCar Recherches Cliniques Inc. (St-Lambert)
Saint-Lambert, Quebec, J4P 1S9
Recruiting
Name
Boehringer Ingelheim
Role
CONTACT
Phone:
18336022346
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