A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Last updated:
2026-07-25
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View trial details

Overview

Official protocol title:

A PHASE 3, 24-WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLELARM EFFICACY AND SAFETY STUDY WITH OPEN-LABEL EXTENSION OF BLU-5937 IN ADULT PARTICIPANTS WITH REFRACTORY CHRONIC COUGH INCLUDING UNEXPLAINED CHRONIC COUGH (CALM-2)

Intervention/treatment:
CAMLIPIXANT (GSK5464714, BLU-5937)
Medical condition:
CHRONIC COUGH
Protocol code:
BUS-P3-02
Control number:
294230
Status:
Active, not recruiting
Approved:
February 11, 2025
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT05600777
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years to 80 Years
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Center
Role
CONTACT
Phone:
+44 (0) 20 89904466
Sponsor
BELLUS HEALTH INC

Locations

GSK Investigational Site
Burlington, ON L7N 3V2

Alberta

GSK Investigational Site
Calgary, Alberta, T2N 1N4
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
George Philteos
Role
PRINCIPAL_INVESTIGATOR

Ontario

GSK Investigational Site
Ajax, Ontario, L1S 2J5
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Richard Tytus
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Hamilton, Ontario, L8L 5G4
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Imran Satia
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Hamilton, Ontario, L8N 3Z5
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Kenneth R. Chapman
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Toronto, Ontario, M5T 3A9
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Giuseppe Mazza
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Windsor, Ontario, N8X 1T3
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Caroline Rheaume
Role
PRINCIPAL_INVESTIGATOR

Quebec

GSK Investigational Site
Montreal, Quebec, H1Y3H5
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Remi Gagnon
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Québec, Quebec, G1V 4T3
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Bonavuth Pek
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Québec, Quebec, G1V 4W2
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Pierre Alexandre Menard
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Saint-Charles-Borromée, Quebec, J6E 2B4
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Ethel Bellavance
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Trois-Rivières, Quebec, G8T 7A1
RECRUITING
Name
US GSK Clinical Trials Call Center
Role
CONTACT
Phone:
877-379-3718
Name
EU GSK Clinical Trials Call Centre
Role
CONTACT
Phone:
+44 (0) 20 8990 4466
Name
Pat Killorn
Role
PRINCIPAL_INVESTIGATOR
GSK Investigational Site
Victoriaville, Quebec, G6P 3Z8
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