Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Last updated:
2026-07-18
Language and content disclaimer

The content and search results on this site are collected from or provided by third parties. As such some of the information may only be available in the language originally submitted by the sponsor of the trial. Learn more about the information on the search portal.

Linking to Non-Government of Canada Websites

Links to websites not under the control of the Government of Canada, including those to our social media accounts, and to clinical trial records in international registries are provided solely for the convenience of our website visitors. We are not responsible for the accuracy, currency or reliability of the content of such websites. The Government of Canada does not offer any guarantee in that regard and is not responsible for the information found through these links, nor does it endorse the sites and their content.

Visitors should also be aware that information offered by non-Government of Canada sites to which this website links is not subject to the Privacy Act or the Official Languages Act and may not be accessible to persons with disabilities. The information offered may be available only in the language(s) used by the sites in question. With respect to privacy, visitors should research the privacy policies of these non-government websites before providing personal information.

View trial details

Overview

Official protocol title:

A RANDOMIZED PHASE III CLINICAL TRIAL FOR THE ADDITION OF DOCETAXEL TO ANDROGEN RECEPTOR PATHWAY INHIBITORS IN PATIENTS WITH METASTATIC CASTRATION SENSITIVE PROSTATE CANCER AND SUBOPTIMAL PSA RESPONSE (TRIPLE-SWITCH)

Intervention/treatment:
DOCETAXEL
Medical condition:
CASTRATION RESISTANT PROSTATE CANCER
Protocol code:
PR.26
Control number:
292424
Status:
Recruiting
Approved:
December 16, 2024
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT06592924
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: MALE
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Mariam Jafri
Role
CONTACT
Phone:
613-533-6430
Name
Wendy Parulekar
Role
CONTACT
Phone:
613-533-6430
Sponsor
CANADIAN CANCER TRIALS GROUP, CANCER RESEARCH INSTITUTE, QUEEN'S UNIVERSITY

Locations

Alberta

Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
780-432-8500
Name
Michael P. Kolinsky
Role
PRINCIPAL_INVESTIGATOR

British Columbia

BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, V5Z 4E6
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
888-939-3333
Name
Corinne Maurice Dror
Role
PRINCIPAL_INVESTIGATOR

Manitoba

CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
866-561-1026
Name
Hanbo Zhang
Role
PRINCIPAL_INVESTIGATOR

New Brunswick

Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, E2L 4L2
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
506-648-6890
Extension 2401
Name
Samantha L. Gray
Role
PRINCIPAL_INVESTIGATOR

Ontario

Health Sciences North
Greater Sudbury, Ontario, P3E 5J1
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
706-522-6237
Extension 2401
Name
Eoghan R. Malone
Role
PRINCIPAL_INVESTIGATOR
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
905-387-9495
Name
Sebastien J. Hotte
Role
PRINCIPAL_INVESTIGATOR
Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
613-549-6666
Name
Martin Smoragiewicz
Role
PRINCIPAL_INVESTIGATOR
London Regional Cancer Program
London, Ontario, N6A 4L6
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
519-685-8600
Name
Lorin Dodbiba
Role
PRINCIPAL_INVESTIGATOR
Niagara Health System-Saint Catharines General
Saint Catharines, Ontario, L2S 0A9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
905-682-6451
Name
David W. Wasserman
Role
PRINCIPAL_INVESTIGATOR
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
416-480-5000
Name
Daniel J. Khalaf
Role
PRINCIPAL_INVESTIGATOR
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, K1H 8L6
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
613-761-4395
Name
Michael Ong
Role
PRINCIPAL_INVESTIGATOR
Trillium Health Partners - Credit Valley Hospital
Mississauga, Ontario, L5M 2N1
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
905-813-4040
Name
Daniel Yokom
Role
PRINCIPAL_INVESTIGATOR
University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
416-946-4501
Name
Di Maria Jiang
Role
PRINCIPAL_INVESTIGATOR
Waterloo Regional Health Network
Kitchener, Ontario, N2G 1G3
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
519-749-4370
Name
Anupam Batra
Role
PRINCIPAL_INVESTIGATOR

Quebec

CHA Hopital L'Enfant-Jesus
Québec, Quebec, G1J 1Z4
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
888-823-5923
Name
Eric Levesque
Role
PRINCIPAL_INVESTIGATOR
CIUSSSEMTL-Hopital Maisonneuve-Rosemont
Montreal, Quebec, H1T 2M4
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
514-252-3400
Extension 3329
Name
Caroline Letendre
Role
PRINCIPAL_INVESTIGATOR
CSSS Champlain-Charles Le Moyne
Greenfield Park, Quebec, J4V 2H1
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
450-466-5065
Extension 3329
Name
Trung N. Nguyen
Role
PRINCIPAL_INVESTIGATOR
Jewish General Hospital
Montreal, Quebec, H3T 1E2
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
514-340-8222
Extension 8248
Name
April Rose
Role
PRINCIPAL_INVESTIGATOR

Saskatchewan

Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
306-655-2914
Name
Nayyer Iqbal
Role
PRINCIPAL_INVESTIGATOR
Did you find what you were looking for?

Contacts and resources