A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

Last updated:
2026-07-18
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View trial details

Overview

Official protocol title:

EFFICACY AND SAFETY OF CO-ADMINISTERED CAGRILINTIDE AND SEMAGLUTIDE (CAGRISEMA) S.C. IN DOSES 2.4/2.4 MG AND 1.0/1.0 MG ONCE WEEKLY VERSUS SEMAGLUTIDE 2.4 MG AND 1.0 MG, CAGRILINTIDE 2.4 MG AND PLACEBO IN PARTICIPANTS WITH TYPE 2 DIABETES INADEQUATELY CONTROLLED ON METFORMIN WITH OR WITHOUT AN SGLT2 INHIBITOR

Intervention/treatment:
CAGRILINTIDE-SEMAGLUTIDE/ CAGRILINTIDE/ SEMAGLUTIDE
Medical condition:
TYPE 2 DIABETES
Protocol code:
NN9388-4896
Control number:
275057
Status:
Closed
Approved:
July 17, 2023
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT06065540
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Sponsor
NOVO NORDISK CANADA INC

Locations

Alberta

Centricity Research Calgary
Calgary, Alberta, T2H 2G4
Centricity Research Calgary Endocrinology
Calgary, Alberta, T2H 2G4
Synergy Wellness Clinic
Sherwood Park, Alberta, T8H 0N2

British Columbia

Guilford Med Clinic
Surrey, British Columbia, V3R 4H6
Hilltop Medical Clinic
Surrey, British Columbia, V4A 0C1
Ocean West Research Clinic
Surrey, British Columbia, V3Z 2N6
Spectrum Health Clinic
Vancouver, British Columbia, V6Z 2T1
TLC Diabetes and Endocrinology
Surrey, British Columbia, V3T0X6

New Brunswick

G.A. Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7

Ontario

Centre de Recherche Saint-Louis
Québec, Ontario, G1W 4R4
Centricity Res. Barrie Endo
Barrie, Ontario, L4N 7L3
Centricity Research Brampton Endocrinology
Brampton, Ontario, L6S 0C6
Centricity Research Etobicoke Endocrinology
Etobicoke, Ontario, M9R 4E1
Centricity Research Oshawa
Oshawa, Ontario, L1J 2K9
Centricity Research Ottawa LMC
Nepean, Ontario, K2J 0V2
Centricity Research Toronto
Toronto, Ontario, M4G 3E8
Centricity Research Vaughn Endocrinology
Concord, Ontario, L4K 4M2
Clinique des Maladies Lipidiques de Quebec Inc.
Québec, Ontario, G1V 4W2
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
Medical Trust Clinics, Inc.
Courtice, Ontario, L1E2J5
Milestone Research
London, Ontario, N5W 6A2
My Endo Diabetes & Endo Cent
Markham, Ontario, L3P 7P2
Western Univ. Cnt for Studies in Fam Med
London, Ontario, N6G 2M1

Quebec

ALPHA Recherche Clinique
Québec, Quebec, G3K 2P8
Centre Medical Acadie
Montreal, Quebec, H4N 2W2
Centricity Res Pointe-Claire
Pointe-Claire, Quebec, H9R 4S3
Ctr de Med Metab de Lanaudiere
Terrebonne, Quebec, J6X 4P7
Diex Recherche Quebec
Québec, Quebec, G1V 4T3
Diex Recherche Victoriaville
Victoriaville, Quebec, G6P 3Z8
LMC Clin Rsrch Inc. (Montreal)
Saint-Laurent, Quebec, H4T 1Z9
Q & T Research Sherbrooke Inc.
Sherbrooke, Quebec, J1J 2G2
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