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View trial details
Overview
Official protocol title:
A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ABELACIMAB IN HIGH-RISK PATIENTS WITH ATRIAL FIBRILLATION WHO HAVE BEEN DEEMED UNSUITABLE FOR ORAL ANTICOAGULATION (LILAC), VERSION 1.0 DATED 18 OCTOBER 2022
Intervention/treatment:
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
ABELACIMAB (MAA868)
Medical condition:
The disease or condition that's being studied in the clinical trial.
Protocol code:
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
ANT-010
Control number:
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
270543
Status:
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site.
• Recruiting - Participants are currently being recruited.
• Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled.
• On hold - The clinical trial has been temporarily stopped, but it may start again.
• Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again.
• Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor.
• No match, ongoing - Please contact sponsor for status information.
• Other - Please contact sponsor for status information.
Recruiting
Approved:
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
January 19, 2023
Trial phase:
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
Phase 3
For more information:
ClinicalTrials.gov -
NCT05712200
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Accepts healthy volunteers:
No
Locations
Anthos Investigative Site 2004
New Westminster, V3L 3W4
WITHDRAWN
Anthos Investigative Site 2005
Halifax, B3H 3A7
Recruiting
Anthos Investigative Site 2006
Saint-Jérôme, J7Z 5T3
WITHDRAWN
Anthos Investigative Site 2014
Montreal, H1T 1C8
Recruiting
Anthos Investigative Site 2015
Edmonton, T6G 2G3
Recruiting
Anthos Investigative Site 2017
Toronto, M4N 3M5
Recruiting
Anthos Investigative Site 2018
Greenfield Park, J4V 2H1
Recruiting
Anthos Investigative Site 2020
Toronto, M4N 3M5
Recruiting
Anthos Investigative Site 2021
North Vancouver, V7M 2H4
Recruiting
Anthos Investigative Site 2022
Thunder Bay, P7B 5N3
Recruiting
Anthos Investigative Site 2023
Toronto, M5S 1B2
Recruiting
Anthos Investigative Site 2024
Saint Catharines, L2P 2W8
Recruiting
Anthos Investigative Site 2025
Hamilton, L8L 2X2
Recruiting
Anthos Investigative Site 2026
Hamilton, L8N 4A6
Recruiting
Anthos Investigative Site 2027
Terrebonne, J6V 2H2
Recruiting
Anthos Investigative Site 2028
Markham, L3P7P3
Recruiting
Nova Scotia
Anthos Investigative Site 2002
Québec, Nova Scotia, G1R 2J6
Recruiting
Anthos Investigative Site 2012
Mira Road, Nova Scotia, B1M DA1
Recruiting
Ontario
Anthos Investigational site 2029
London, Ontario, N6A 5A5
Recruiting
Anthos Investigative Site 2003
Cambridge, Ontario, N1R 7R1
Recruiting
Anthos Investigative Site 2016
Abbotsford British Columbia, Ontario, V2S 0C2
Recruiting
Quebec
Anthos Investigative Site 2007
Chicoutimi, Quebec, G7H 5H6
Recruiting
Anthos Investigative Site 2010
Sherbrooke, Quebec, J1H 5N4
Recruiting
Anthos Investigative Site 2019
Brampton, Quebec, L6R 3J7
WITHDRAWN