Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Last updated:
2026-07-18
Language and content disclaimer

The content and search results on this site are collected from or provided by third parties. As such some of the information may only be available in the language originally submitted by the sponsor of the trial. Learn more about the information on the search portal.

Linking to Non-Government of Canada Websites

Links to websites not under the control of the Government of Canada, including those to our social media accounts, and to clinical trial records in international registries are provided solely for the convenience of our website visitors. We are not responsible for the accuracy, currency or reliability of the content of such websites. The Government of Canada does not offer any guarantee in that regard and is not responsible for the information found through these links, nor does it endorse the sites and their content.

Visitors should also be aware that information offered by non-Government of Canada sites to which this website links is not subject to the Privacy Act or the Official Languages Act and may not be accessible to persons with disabilities. The information offered may be available only in the language(s) used by the sites in question. With respect to privacy, visitors should research the privacy policies of these non-government websites before providing personal information.

View trial details

Overview

Official protocol title:

A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ABELACIMAB IN HIGH-RISK PATIENTS WITH ATRIAL FIBRILLATION WHO HAVE BEEN DEEMED UNSUITABLE FOR ORAL ANTICOAGULATION (LILAC), VERSION 1.0 DATED 18 OCTOBER 2022

Intervention/treatment:
ABELACIMAB (MAA868)
Medical condition:
ATRIAL FIBRILLATION
Protocol code:
ANT-010
Control number:
270543
Status:
Recruiting
Approved:
January 19, 2023
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT05712200
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
65 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Anthos Therapeutics a Novartis Company
Role
CONTACT
Phone:
1-888-669-6682
Sponsor
ANTHOS THERAPEUTICS, INC.

Locations

Anthos Investigative Site 2004
New Westminster, V3L 3W4
WITHDRAWN
Anthos Investigative Site 2005
Halifax, B3H 3A7
Recruiting
Anthos Investigative Site 2006
Saint-Jérôme, J7Z 5T3
WITHDRAWN
Anthos Investigative Site 2014
Montreal, H1T 1C8
Recruiting
Anthos Investigative Site 2015
Edmonton, T6G 2G3
Recruiting
Anthos Investigative Site 2017
Toronto, M4N 3M5
Recruiting
Anthos Investigative Site 2018
Greenfield Park, J4V 2H1
Recruiting
Anthos Investigative Site 2020
Toronto, M4N 3M5
Recruiting
Anthos Investigative Site 2021
North Vancouver, V7M 2H4
Recruiting
Anthos Investigative Site 2022
Thunder Bay, P7B 5N3
Recruiting
Anthos Investigative Site 2023
Toronto, M5S 1B2
Recruiting
Anthos Investigative Site 2024
Saint Catharines, L2P 2W8
Recruiting
Anthos Investigative Site 2025
Hamilton, L8L 2X2
Recruiting
Anthos Investigative Site 2026
Hamilton, L8N 4A6
Recruiting
Anthos Investigative Site 2027
Terrebonne, J6V 2H2
Recruiting
Anthos Investigative Site 2028
Markham, L3P7P3
Recruiting

Nova Scotia

Anthos Investigative Site 2002
Québec, Nova Scotia, G1R 2J6
Recruiting
Anthos Investigative Site 2012
Mira Road, Nova Scotia, B1M DA1
Recruiting

Ontario

Anthos Investigational site 2029
London, Ontario, N6A 5A5
Recruiting
Anthos Investigative Site 2003
Cambridge, Ontario, N1R 7R1
Recruiting
Anthos Investigative Site 2016
Abbotsford British Columbia, Ontario, V2S 0C2
Recruiting

Quebec

Anthos Investigative Site 2007
Chicoutimi, Quebec, G7H 5H6
Recruiting
Anthos Investigative Site 2010
Sherbrooke, Quebec, J1H 5N4
Recruiting
Anthos Investigative Site 2019
Brampton, Quebec, L6R 3J7
WITHDRAWN
Did you find what you were looking for?