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View trial details
Overview
Official protocol title:
HERMES: EFFECTS OF ZILTIVEKIMAB VERSUS PLACEBO ON MORBIDITY AND MORTALITY IN PATIENTS WITH HEART FAILURE WITH MILDLY REDUCED OR PRESERVED EJECTION FRACTION AND SYSTEMIC INFLAMMATION
Intervention/treatment:
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
ZILTIVEKIMAB
Medical condition:
The disease or condition that's being studied in the clinical trial.
HEART FAILURE WITH PRESERVED EJECTION FRACTION
Protocol code:
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
EX6018-4915
Control number:
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
268152
Status:
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site.
• Recruiting - Participants are currently being recruited.
• Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled.
• On hold - The clinical trial has been temporarily stopped, but it may start again.
• Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again.
• Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor.
• No match, ongoing - Please contact sponsor for status information.
• Other - Please contact sponsor for status information.
Active, not recruiting
Approved:
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
December 20, 2022
Trial phase:
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
Phase 3
For more information:
ClinicalTrials.gov -
NCT05636176
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Accepts healthy volunteers:
No
Locations
Alberta
Alta Clinical Research
Edmonton, Alberta, T5A 4L8
RECRUITING
University of Calgary_Calgary
Calgary, Alberta, T2N 4Z6
RECRUITING
British Columbia
Ctr for Cardiovascular Innovation
Vancouver, British Columbia, V5Z 1M9
RECRUITING
North Shore Heart Centre
North Vancouver, British Columbia, V7M 2H4
RECRUITING
Royal Columbian Hospital
New Westminster, British Columbia, V3L 3W4
RECRUITING
SMH Cardiology Clinical Trials Inc.
Surrey, British Columbia, V3V 0C6
NOT_YET_RECRUITING
St Pauls Hospital
Vancouver, British Columbia, V6Z1Y6
RECRUITING
Victoria Heart Institute Foundation
Victoria, British Columbia, V8R 1B2
RECRUITING
Manitoba
St. Boniface Hospital
Winnipeg, Manitoba, R2H 2HA6
RECRUITING
New Brunswick
G.A. Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7
RECRUITING
Nova Scotia
Nova Scotia Health
Halifax, Nova Scotia, B3H 3A7
RECRUITING
Ontario
Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6
RECRUITING
Centricity Research Oshawa
Oshawa, Ontario, L1J 2K9
RECRUITING
Clinical Research Solutions Inc.
Waterloo, Ontario, N2T 0C1
RECRUITING
CPS Research
Waterloo, Ontario, N2T 0C1
RECRUITING
Dawson Clinical Research
Guelph, Ontario, N1H 1B1
RECRUITING
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
RECRUITING
Hamilton Hlth Sc. - General Site
Hamilton, Ontario, L8L 2X2
RECRUITING
Health Sciences North Rsrch Inst
Greater Sudbury, Ontario, P3E 5J1
RECRUITING
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2
RECRUITING
North York Diagn & Cardiac Ctr
North York, Ontario, M6B 3H7
RECRUITING
Partnrs Adv Cardio Eval (PACE)
Newmarket, Ontario, L3Y 2P6
RECRUITING
Saul Vizel Pro. Med. Corp
Cambridge, Ontario, N1R 7R1
RECRUITING
St. Joseph's Hospital
London, Ontario, N6A 4V2
RECRUITING
St. Michael's - Division of Cardiology
Toronto, Ontario, M5B 1W8
RECRUITING
Winchester Dist Memorial Hosp
Winchester, Ontario, K0C 2K0
RECRUITING
Women's College Hospital
Toronto, Ontario, M5S 1B1
RECRUITING
Quebec
CardioVasc HR Inc
Saint-Jean-sur-Richelieu, Quebec, J3A 1J2
RECRUITING
CHU de Montréal
Montreal, Quebec, H2X 0C1
RECRUITING
CISSSL Hôsp Pierre-Le Gardeur
Terrebonne, Quebec, J6V 2H2
COMPLETED
CIUSSS de l'E CHUS_Sherbrooke
Sherbrooke, Quebec, J1G 2E8
COMPLETED
Ctr de méd métab de Lanaudière
Terrebonne, Quebec, J6X 4P7
COMPLETED
Diex Recherche Trois-Rivieres
Trois-Rivières, Quebec, G9A 4P3
RECRUITING
Institut de Cardiologie de Montreal
Montreal, Quebec, H1T 1C8
RECRUITING
Viacar Recherche Clinique Inc.
Longueuil, Quebec, J4H4B9
RECRUITING
Saskatchewan
Royal University Hospital
Saskatoon, Saskatchewan, S7N 0W8
RECRUITING