A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

Last updated:
2026-07-18
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View trial details

Overview

Official protocol title:

HERMES: EFFECTS OF ZILTIVEKIMAB VERSUS PLACEBO ON MORBIDITY AND MORTALITY IN PATIENTS WITH HEART FAILURE WITH MILDLY REDUCED OR PRESERVED EJECTION FRACTION AND SYSTEMIC INFLAMMATION

Intervention/treatment:
ZILTIVEKIMAB
Medical condition:
HEART FAILURE WITH PRESERVED EJECTION FRACTION
Protocol code:
EX6018-4915
Control number:
268152
Status:
Active, not recruiting
Approved:
December 20, 2022
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT05636176
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Novo Nordisk
Role
CONTACT
Phone:
(+1) 866-867-7178
Sponsor
NOVO NORDISK CANADA INC

Locations

Alberta

Alta Clinical Research
Edmonton, Alberta, T5A 4L8
RECRUITING
University of Calgary_Calgary
Calgary, Alberta, T2N 4Z6
RECRUITING

British Columbia

Ctr for Cardiovascular Innovation
Vancouver, British Columbia, V5Z 1M9
RECRUITING
North Shore Heart Centre
North Vancouver, British Columbia, V7M 2H4
RECRUITING
Royal Columbian Hospital
New Westminster, British Columbia, V3L 3W4
RECRUITING
SMH Cardiology Clinical Trials Inc.
Surrey, British Columbia, V3V 0C6
NOT_YET_RECRUITING
St Pauls Hospital
Vancouver, British Columbia, V6Z1Y6
RECRUITING
Victoria Heart Institute Foundation
Victoria, British Columbia, V8R 1B2
RECRUITING

Manitoba

St. Boniface Hospital
Winnipeg, Manitoba, R2H 2HA6
RECRUITING

New Brunswick

G.A. Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7
RECRUITING

Nova Scotia

Nova Scotia Health
Halifax, Nova Scotia, B3H 3A7
RECRUITING

Ontario

Cambridge Cardiac Care Centre
Cambridge, Ontario, N1R 6V6
RECRUITING
Centricity Research Oshawa
Oshawa, Ontario, L1J 2K9
RECRUITING
Clinical Research Solutions Inc.
Waterloo, Ontario, N2T 0C1
RECRUITING
CPS Research
Waterloo, Ontario, N2T 0C1
RECRUITING
Dawson Clinical Research
Guelph, Ontario, N1H 1B1
RECRUITING
Diabetes Heart Research Centre
Toronto, Ontario, M6G 1M2
RECRUITING
Hamilton Hlth Sc. - General Site
Hamilton, Ontario, L8L 2X2
RECRUITING
Health Sciences North Rsrch Inst
Greater Sudbury, Ontario, P3E 5J1
RECRUITING
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2
RECRUITING
North York Diagn & Cardiac Ctr
North York, Ontario, M6B 3H7
RECRUITING
Partnrs Adv Cardio Eval (PACE)
Newmarket, Ontario, L3Y 2P6
RECRUITING
Saul Vizel Pro. Med. Corp
Cambridge, Ontario, N1R 7R1
RECRUITING
St. Joseph's Hospital
London, Ontario, N6A 4V2
RECRUITING
St. Michael's - Division of Cardiology
Toronto, Ontario, M5B 1W8
RECRUITING
Winchester Dist Memorial Hosp
Winchester, Ontario, K0C 2K0
RECRUITING
Women's College Hospital
Toronto, Ontario, M5S 1B1
RECRUITING

Quebec

CardioVasc HR Inc
Saint-Jean-sur-Richelieu, Quebec, J3A 1J2
RECRUITING
CHU de Montréal
Montreal, Quebec, H2X 0C1
RECRUITING
CISSSL Hôsp Pierre-Le Gardeur
Terrebonne, Quebec, J6V 2H2
COMPLETED
CIUSSS de l'E CHUS_Sherbrooke
Sherbrooke, Quebec, J1G 2E8
COMPLETED
Ctr de méd métab de Lanaudière
Terrebonne, Quebec, J6X 4P7
COMPLETED
Diex Recherche Trois-Rivieres
Trois-Rivières, Quebec, G9A 4P3
RECRUITING
Institut de Cardiologie de Montreal
Montreal, Quebec, H1T 1C8
RECRUITING
Viacar Recherche Clinique Inc.
Longueuil, Quebec, J4H4B9
RECRUITING

Saskatchewan

Royal University Hospital
Saskatoon, Saskatchewan, S7N 0W8
RECRUITING
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