Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

Last updated:
2026-10-03
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View trial details

Overview

Official protocol title:

PHASE III RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF METFORMIN FOR COGNITIVE RECOVERY AND WHITE MATTER GROWTH IN PAEDIATRIC PATIENTS WITH A BRAIN TUMOUR

Intervention/treatment:
METFORMIN
Medical condition:
MEDULLOBLASTOMA
Protocol code:
METMEDCAN
Control number:
260451
Status:
Recruiting
Approved:
February 15, 2022
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT05230758
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
7 Years to 21 Years
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Lauren Cole, PhD
Role
CONTACT
Phone:
416-813-7396
Extension 307396
Sponsor
HOSPITAL FOR SICK CHILDREN

Locations

Alberta

Alberta Children's Hospital
Calgary, Alberta, T3B 6A8
Recruiting
Name
Lucie Lafay-Cousin, MD
Role
CONTACT
Phone:
403-955-2554
Name
Sherry Qian
Role
CONTACT
Phone:
403-955-7263
Stollery Children's Hospital
Edmonton, Alberta, T6G 2B7
Recruiting
Name
Liana Nobre, MD
Role
CONTACT
Phone:
780-407-8798

British Columbia

Children's & Women's Health Centre of British Columbia
Vancouver, British Columbia, V6H 3V4
Recruiting
Name
Sylvia Cheng, MD
Role
CONTACT
Phone:
604-875-2406
Name
Alecia Lim
Role
CONTACT
Phone:
604-875-2345
Extension 5262

Manitoba

Cancer Care Manitoba
Winnipeg, Manitoba, R3E 0V9
Recruiting
Name
Magimairajan I Vanan, MD
Role
CONTACT
Phone:
204-787-4724
Name
Clinical Trial Unit CTU
Role
CONTACT
Phone:
204-787-4156

Nova Scotia

Izaak Walton Killam (IWK) Health Centre
Halifax, Nova Scotia, B3K 6R8
Recruiting
Name
Bruce Crooks, MD
Role
CONTACT
Phone:
902-470-6500
Name
Jennifer Curran
Role
CONTACT
Phone:
902-470-8048

Ontario

Children's Hospital, London Health Sciences Centre
London, Ontario, N6A 5W9
Recruiting
Name
Shayna Zelcer, MD
Role
CONTACT
Phone:
519-685-8500
Extension 52678
Children's Hospital of Eastern Ontario
Ottawa, Ontario, K1H 8L1
Recruiting
Name
Donna Johnston, MD
Role
CONTACT
Phone:
613-737-7600
Extension 2210
Hamilton Health Sciences - McMaster Children's Hospital
Hamilton, Ontario, L8S 4K1
Recruiting
Name
Adam Fleming, MD
Role
CONTACT
Phone:
905-521-2100
Extension 76720
The Hospital for Sick Children
Toronto, Ontario, M5G 1X8
Recruiting
Name
Vijay Ramaswamy, MD
Role
CONTACT
Phone:
416-813-7654
Extension 208221
Name
Lauren Cole, PhD
Role
CONTACT
Phone:
416-813-7396
Extension 307396

Quebec

CHU de Québec - Université Laval
Quebec, Quebec, G1V 4G2
Recruiting
Name
Larouche Valérie, MD
Role
CONTACT
Phone:
418-525-4444
Extension 40121
Name
General Contact
Role
CONTACT
CHU de Sherbrooke
Sherbrooke, Quebec, J1G 2E8
Recruiting
Name
Stéphanie Vairy, MD
Role
CONTACT
Phone:
819-346-1110
Extension 7-3068
CHU Sainte-Justine
Montreal, Quebec, H3T 1C5
Recruiting
Name
Sébastien Perreault, MD
Role
CONTACT
Phone:
514-345-4931
Extension 5019
Montreal Children's Hospital
Montreal, Quebec, H4A 3J1
Recruiting
Name
Geneviève Legault, MD
Role
CONTACT
Phone:
514-412-4445

Saskatchewan

Saskatchewan Health Authority
Saskatoon, Saskatchewan, S7N 0W8
Recruiting
Name
Kathleen Felton, MD
Role
CONTACT
Phone:
306-655-2733
Name
Jessica Marien
Role
CONTACT
Phone:
306-655-3544
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