Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma

Last updated:
2026-07-18
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View trial details

Overview

Official protocol title:

A RANDOMIZED PHASE II TRIAL OF PEMBROLIZUMAB AND BRENTUXIMAB VEDOTIN VERSUS GDP FOLLOWED BY HIGH DOSE CHEMOTHERAPY AND AUTOLOGOUS STEM CELL TRANSPLANTATION FOR RELAPSED/REFRACTORY CLASSICAL HODGKIN LYMPHOMA

Intervention/treatment:
ADCETRIS / KEYTRUDA
Medical condition:
HODGKIN LYMPHOMA
Protocol code:
CCTG: HD.11
Control number:
259384
Status:
Recruiting
Approved:
January 21, 2022
Trial phase:
Phase 2
For more information:
ClinicalTrials.gov - NCT05180097
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Annette Hay
Role
CONTACT
Phone:
613-533-6430
Name
Lois Shepherd
Role
CONTACT
Phone:
613-533-6430
Sponsor
CANADIAN CANCER TRIALS GROUP, CANCER RESEARCH INSTITUTE, QUEEN'S UNIVERSITY

Locations

Alberta

Arthur J.E. Child Comprehensive Cancer Centre
Calgary, Alberta, T2N 5G2
Recruiting
Name
Robert Puckrin
Role
CONTACT
Phone:
403 944-5222

British Columbia

BCCA - Vancouver
Vancouver, British Columbia, V5Z 4E6
Recruiting
Name
Kerry J. Savage
Role
CONTACT
Phone:
604 877-6000
Extension 2641

Newfoundland and Labrador

Dr. H. Bliss Murphy Cancer Centre
St. John's, Newfoundland and Labrador, A1B 3V6
Recruiting
Name
Jacqueline Costello
Role
CONTACT
Phone:
709 777-6545

Nova Scotia

QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 1V7
Recruiting
Name
Mary-Margaret Keating
Role
CONTACT
Phone:
902 473-7006

Ontario

Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2
Recruiting
Name
Amaris Balitsky
Role
CONTACT
Phone:
905 387-9495
London Health Sciences Centre Research Inc.
London, Ontario, N6A 5W9
Recruiting
Name
Joy Elise Mangel
Role
CONTACT
Phone:
519 685-8500
Extension 52391
Ottawa Hospital Research Institute
Ottawa, Ontario, K1H 8L6
Recruiting
Name
Isabelle Bence-Bruckler
Role
CONTACT
Phone:
613 737-8152
University Health Network
Toronto, Ontario, M5G 2M9
Recruiting
Name
John Kuruvilla
Role
CONTACT
Phone:
416 946-2827

Quebec

CIUSSS de l'Estrie - Centre hospitalier
Sherbrooke, Quebec, J1H 5N4
Recruiting
Name
Stephanie Desilets
Role
CONTACT
Phone:
819 346-1110
Extension 74816
The Jewish General Hospital
Montreal, Quebec, H3T 1E2
Recruiting
Name
Nathalie Johnson
Role
CONTACT
Phone:
514 398-8307
The Research Institute of the McGill University
Montreal, Quebec, H4A 3J1
Recruiting
Name
Kelly Davison
Role
CONTACT
Phone:
514 934-1934
Extension 31558

Saskatchewan

Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Recruiting
Name
Muhammad Salim
Role
CONTACT
Phone:
306 766-2691
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