EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)
Last updated:
Last updated
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2026-07-11
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EMPACT-MI: A STREAMLINED, MULTICENTRE, RANDOMISED, PARALLEL GROUP, DOUBLEBLIND PLACEBO-CONTROLLED SUPERIORITY TRIAL TO EVALUATE THE EFFECT OF EMPAGLIFLOZIN ON HOSPITALISATION FOR HEART FAILURE AND MORTALITY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
Intervention/treatment:
Intervention/treatment
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
EMPAGLIFLOZIN
Medical condition:
Medical condition
The disease or condition that's being studied in the clinical trial.
ACUTE MYOCARDIAL INFARCTION
Protocol code:
Protocol Code
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
1245-0202
Control number:
Control number
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
245409
Status:
Trial Status
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site. • Recruiting - Participants are currently being recruited. • Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled. • On hold - The clinical trial has been temporarily stopped, but it may start again. • Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again. • Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor. • No match, ongoing - Please contact sponsor for status information. • Other - Please contact sponsor for status information.
Closed
Approved:
Approved
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
December 16, 2020
Date Completed:
Date completed
The date of the last participant’s last visit in the global study. The completion date may be actual or estimated, depending what was provided to the registry. Estimated completion dates may be in the past or future.
Trial phase:
Trial phase
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Age
18 Years and older
Accepts healthy volunteers:
No
Contacts and locations
Contact
Contact
Information for an individual or organisation that can respond to questions about this clinical trial. This information comes from the international registry.
The sponsor conducts the clinical trial and is responsible for every aspect. For example this could be a company, a university or an individual researcher.
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Locations
Alberta
Heritage Medical Research Clinic
Calgary, Alberta, T2N 4Z6
Royal Alexandra Hospital
Edmonton, Alberta, T5H 3V9
University of Alberta Hospital (University of Alberta)
Edmonton, Alberta, T6G 2B7
British Columbia
Oakville Trafalgar Memorial Hospital
Oakville, British Columbia, L6M 0L8
Royal Inland Hospital
Kamloops, British Columbia, V2C 2T1
Surrey Memorial Hospital
Surrey, British Columbia, V3V 0C6
Vancouver General Hospital
Vancouver, British Columbia, V5Z 1M9
Victoria Heart Institute Foundation
Victoria, British Columbia, V8R 1B2
Manitoba
St. Boniface Hospital
Winnipeg, Manitoba, R2H 2A6
New Brunswick
GA Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7
Nova Scotia
QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 3A7
Ontario
Heart Health Institute
Scarborough Village, Ontario, M1B 4Z8
One Heart Care Ventures
Mississauga, Ontario, L4Y 1M3
Peterborough Regional Health Centre
Peterborough, Ontario, K9J 7C6
Queen's University
Kingston, Ontario, K7L 2V7
Southlake Regional Health Centre
Newmarket, Ontario, L3Y 2P7
William Osler Health Centre
Brampton, Ontario, L6R 3J7
Women's College Hospital
Toronto, Ontario, M5S 1B2
Quebec
Centre Hospitalier de l'Universite de Montreal (CHUM)
Montreal, Quebec, H2X 0A9
CIUSSS de la Mauricie-et-du-Centre-du-Quebec
Trois-Rivières, Quebec, G8Z 3R9
CIUSSS de l Estrie-CHUS
Sherbrooke, Quebec, J1H 5N4
CSSS du Sud de Lanaudiere - Hopital Pierre-Le Gardeur
Terrebonne (Lachenaie), Quebec, J6V 2H2
IUCPQ (Laval University)
Sainte-Foy, Quebec, G1V 4G5
McGill University Health Centre (MUHC)
Montreal, Quebec, H4A 3J1
Montreal General Hospital - McGill University Health Centre