A Dose-Ranging Study With Vupanorsen (TRANSLATE-TIMI 70)

Last updated:
2026-07-11
Language and content disclaimer

The content and search results on this site are collected from or provided by third parties. As such some of the information may only be available in the language originally submitted by the sponsor of the trial. Learn more about the information on the search portal.

Linking to Non-Government of Canada Websites

Links to websites not under the control of the Government of Canada, including those to our social media accounts, and to clinical trial records in international registries are provided solely for the convenience of our website visitors. We are not responsible for the accuracy, currency or reliability of the content of such websites. The Government of Canada does not offer any guarantee in that regard and is not responsible for the information found through these links, nor does it endorse the sites and their content.

Visitors should also be aware that information offered by non-Government of Canada sites to which this website links is not subject to the Privacy Act or the Official Languages Act and may not be accessible to persons with disabilities. The information offered may be available only in the language(s) used by the sites in question. With respect to privacy, visitors should research the privacy policies of these non-government websites before providing personal information.

View trial details

Overview

Official protocol title:

A PHASE 2B RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP, DOSE-RANGING STUDY TO ASSESS THE EFFICACY, SAFETY, AND TOLERABILITY OF VUPANORSEN (PF-07285557) IN STATIN-TREATED PARTICIPANTS WITH DYSLIPIDEMIA

Intervention/treatment:
VUPANORSEN (PF-07285557, ISIS 703802)
Medical condition:
DYSLIPIDEAMIA
Protocol code:
C4491011
Control number:
238865
Status:
Closed
Approved:
August 20, 2020
Date Completed:
Trial phase:
Phase 2
For more information:
ClinicalTrials.gov - NCT04516291
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
40 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Pfizer ClinicalTrials.gov Call Center
Organization
Pfizer Inc.
Phone:
1-800-718-1021
Sponsor
PFIZER CANADA ULC

Locations

Alberta

C-endo
Edmonton, Alberta, T6H 2L4
MIC Medical Imaging
Edmonton, Alberta, T6J 5E5
Synergy Medical Clinic
Sherwood Park, Alberta, T8H 0N2

British Columbia

Access MRI
Surrey, British Columbia, V3S 9A5
SMH Cardiology Clinical Trials Inc.
Surrey, British Columbia, V3V 0C6

Nova Scotia

Nova Scotia Health Authority QE II Health Sciences Centre
Halifax, Nova Scotia, B3H 1V7
Nova Scotia Health Authority QE II Health Sciences Centre
Halifax, Nova Scotia, B3H 2Y9

Ontario

Aggarwal and Associates Limited
Brampton, Ontario, L6T 0G1
Bluewater Clinical Research Group Inc.
Sarnia, Ontario, N7T 4X3
Dawson Clinical Research
Guelph, Ontario, N1H 1B1
Devonshire Clinical Research Inc.
Woodstock, Ontario, N4S 5P5
Dr. Anil K. Gupta Medicine Professional Corporation
Toronto, Ontario, M9V 4B4
GNMI Medical Imaging
Mississauga, Ontario, L5R 3K6
GNMI Medical Imaging
Mississauga, Ontario, L5R 3K7
GNMI MRI and CT Medical Imaging
Mississauga, Ontario, L6R 3K7
Holland Bloorview Kids Rehabilitation Hospital
Toronto, Ontario, M4G 1R8
KMH Cardiology Centres Inc.
Kitchener, Ontario, N2M 5N4
LMC Clinical Research Inc. (Barrie)
Barrie, Ontario, L4N 7L3
LMC Clinical Research Inc. (Etobicoke)
Etobicoke, Ontario, M9R 4E1
LMC Clinical Research Inc. (Thornhill)
Concord, Ontario, L4K 4M2
Milestone Research Inc.
London, Ontario, N5W 6A2
North York Diagnostic and Cardiac Centre
North York, Ontario, M6B 3H7
Robarts Research Institute, Western University
London, Ontario, N6A 5B7

Quebec

Alpha Recherche Clinique
Québec, Quebec, G2J 0C4
Centre de Recherche Saint-Louis
Québec, Quebec, G1W4R4
Diex Recherche Joliette
Saint-Charles-Borromée, Quebec, J6E 2B4
Diex Recherche Quebec Inc.
Québec, Quebec, G1N 4V3
Ecogene-21
Chicoutimi, Quebec, G7H 7K9
IRM Quebec - Complexe Synase
Québec, Quebec, G1J 0H4
IRM Quebec Synase
Québec, Quebec, G1J 0H4
Manna Research (Mirabel)
Mirabel, Quebec, J7J 2K8
Montreal Heart Institute
Montreal, Quebec, H1T 1C8
Radimed West Island
Pointe-Claire, Quebec, H9R 4R9
Recherche GCP Research
Montreal, Quebec, H1M 1B1
Research Institute of the McGill University Health Center
Montreal, Quebec, H4A 3J1
Research Institute of the McGill University Health Centre
Montreal, Quebec, H4A 3J1
Resonance Magnetique du Saguenay-Lac-Saint-Jean
Chicoutimi, Quebec, G7H 4J1

Results

See the results from the trial NCT04516291. This is an external link. The information is not authorized by the Government of Canada.

Date posted:
Did you find what you were looking for?

Contacts and resources