S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

Last updated:
2026-07-11
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View trial details

Overview

Official protocol title:

MRI BRAIN SURVEILLANCE ALONE VERSUS MRI SURVEILLANCE AND PROPHYLACTIC CRANIAL IRRADIATION (PCI): A RANDOMIZED PHASE III TRIAL IN SMALL-CELL LUNG CANCER (MAVERICK)

Intervention/treatment:
MEMANTINE
Medical condition:
SMALL CELL LUNG CANCER
Protocol code:
S1827 (CCTG BRC8)
Control number:
238530
Status:
Active, not recruiting
Approved:
May 19, 2020
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT04155034
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Sponsor
CANADIAN CANCER TRIALS GROUP, CANCER RESEARCH INSTITUTE, QUEEN'S UNIVERSITY

Locations

British Columbia

BCCA-Vancouver Island Cancer Centre
Victoria, British Columbia, V8R 6V5
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
604-877-6010
Name
Julianna Caon
Role
PRINCIPAL_INVESTIGATOR

Manitoba

CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
866-561-1026
Name
Bashir M. Bashir
Role
PRINCIPAL_INVESTIGATOR

New Brunswick

Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, E2L 4L2
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
506-648-6890
Name
Farah Naz
Role
PRINCIPAL_INVESTIGATOR

Newfoundland and Labrador

Doctor H. Bliss Murphy Cancer Centre
St. John's, Newfoundland and Labrador, A1B 3V6
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
709-777-7589
Name
Jonathan D. Greenland
Role
PRINCIPAL_INVESTIGATOR

Ontario

Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
905-387-9495
Name
Anand Swaminath
Role
PRINCIPAL_INVESTIGATOR
Lakeridge Health Oshawa
Oshawa, Ontario, L1G 2B9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
905-576-8711
Extension 4258
Name
Joel Broomfield
Role
PRINCIPAL_INVESTIGATOR
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
416-480-5000
Name
Alexander V. Louie
Role
PRINCIPAL_INVESTIGATOR
University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
416-946-4501
Name
Alexander Y. Sun
Role
PRINCIPAL_INVESTIGATOR

Quebec

Centre Hospitalier Regional de Trois-Rivieres
Trois-Rivières, Quebec, G8Z 3R9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
819-697-3333
Extension 64399
Name
Francois Vincent
Role
PRINCIPAL_INVESTIGATOR
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
Sherbrooke, Quebec, J1H 5N4
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
819-820-6480
Name
Guy-Anne Turgeon
Role
PRINCIPAL_INVESTIGATOR
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)
Québec, Quebec, G1R 2J6
Recruiting
Name
Site Public Contact
Role
CONTACT
Name
Caroline Lavoie
Role
PRINCIPAL_INVESTIGATOR
The Research Institute of the McGill University Health Centre (MUHC)
Montreal, Quebec, H3H 2R9
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
514-934-1934
Extension 48354
Name
Bassam S. Abdulkarim
Role
PRINCIPAL_INVESTIGATOR

Saskatchewan

Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Recruiting
Name
Site Public Contact
Role
CONTACT
Phone:
306-766-2213
Name
Dilip D. Panjwani
Role
PRINCIPAL_INVESTIGATOR
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