Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Last updated:
2026-08-01
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View trial details

Overview

Official protocol title:

A MULTICENTER, OPEN LABEL, PHASE III EXTENSION TRIAL TO STUDY THE LONG-TERM SAFETY AND EFFICACY IN PARTICIPANTS WITH ADVANCED TUMORS WHO ARE CURRENTLY ON TREATMENT OR IN FOLLOW-UP IN A PEMBROLIZUMAB TRIAL

Intervention/treatment:
KEYTRUDA / YERVOY / LENVIMA / OLAPARIB / FAVEZELIMAB / MK-4280A
Medical condition:
ADVANCED SOLID TUMORS
Protocol code:
MK-3475-587
Control number:
216413
Status:
Recruiting
Approved:
June 12, 2018
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT03486873
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Toll Free Number
Role
CONTACT
Phone:
1-888-577-8839
Sponsor
MERCK CANADA INC

Locations

Alberta

Arthur J.E. Child Comprehensive Cancer Centre ( Site 2815)
Calgary, Alberta, T2N 5G2
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
(587) 231-6204
Cross Cancer Institute ( Site 2804)
Edmonton, Alberta, T6G 1Z2
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
7804328248

Manitoba

CancerCare Manitoba ( Site 2814)
Winnipeg, Manitoba, R3E 0V9
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
204-787-2197

Ontario

Hamilton Health Sciences-Juravinski Cancer Centre ( Site 2801)
Hamilton, Ontario, L8V 5C2
COMPLETED
Kingston Health Sciences Centre-Kingston General Hospital Site ( Site 2808)
Kingston, Ontario, K7L 2V7
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
6135496666
London Health Sciences Centre ( Site 2806)
London, Ontario, N6A 5W9
COMPLETED
Name
Study Coordinator
Role
CONTACT
Phone:
5196466005
Mount Sinai Hospital ( Site 2811)
Toronto, Ontario, M5G 1X5
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
416-586-5117
Princess Margaret Cancer Centre ( Site 2803)
Toronto, Ontario, M5G 2C4
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
4169462000
Sunnybrook Research Institute ( Site 2802)
Toronto, Ontario, M4N 3M5
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
4164804616
The Ottawa Hospital - General Campus ( Site 2813)
Ottawa, Ontario, K1H 8L6
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
613-737-7700x71985

Quebec

Centre Hospitalier de l Universite de Montreal - CHUM ( Site 2807)
Montreal, Quebec, H2X 3E4
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
5144127512
Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec ( Site 2816)
Trois-Rivières, Quebec, G8Z 3R9
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
8196973333x63238
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 2805)
Québec, Quebec, G1J 1Z4
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
4185254444
Centre Intégré de Santé et de Services Sociaux (CISSS) de La-Centre intégré de cancérologie de Lava ( Site 2810)
Laval, Quebec, H7M 3L9
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
450-668-1010x23671
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre-Oncology ( Site 2809)
Greenfield Park, Quebec, J4V 2H1
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
4504665000
Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 2812)
Sherbrooke, Quebec, J1H 5H4
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
8193461110X12848
McGill University Health Centre ( Site 2818)
Montreal, Quebec, H4A 3J1
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
5149341934
St. Marys Hospital Center ( Site 2820)
Montreal, Quebec, H3T 1M5
RECRUITING
Name
Study Coordinator
Role
CONTACT
Phone:
514-345-3511x3378
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