A Study to Evaluate the Safety and Efficacy of Ruxolitinib Phosphate Cream Applied Topically to Adults With Atopic Dermatitis
Last updated:
Last updated
The date of the most recent update for each trial record in the Canadian Clinical Trial Search Portal.
2026-07-11
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A PHASE 2, RANDOMIZED, DOSE-RANGING, VEHICLE-CONTROLLED AND TRIAMCINOLONE 0.1% CREAM¿CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF INCB018424 PHOSPHATE CREAM APPLIED TOPICALLY TO ADULTS WITH ATOPIC DERMATITIS
Intervention/treatment:
Intervention/treatment
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
RUXOLITINIB (INCB018424)
Medical condition:
Medical condition
The disease or condition that's being studied in the clinical trial.
ATOPIC DERMATITIS
Protocol code:
Protocol Code
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
INCB 18424-206
Control number:
Control number
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
199502
Status:
Trial Status
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site. • Recruiting - Participants are currently being recruited. • Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled. • On hold - The clinical trial has been temporarily stopped, but it may start again. • Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again. • Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor. • No match, ongoing - Please contact sponsor for status information. • Other - Please contact sponsor for status information.
Closed
Approved:
Approved
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
November 18, 2016
Date Completed:
Date completed
The date of the last participant’s last visit in the global study. The completion date may be actual or estimated, depending what was provided to the registry. Estimated completion dates may be in the past or future.
Trial phase:
Trial phase
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Age
18 Years to 70 Years
Accepts healthy volunteers:
No
Contacts and locations
Contact
Contact
Information for an individual or organisation that can respond to questions about this clinical trial. This information comes from the international registry.
The sponsor conducts the clinical trial and is responsible for every aspect. For example this could be a company, a university or an individual researcher.
INCYTE CORPORATION
Locations
Alberta
INSTITUTE FOR SKIN ADVANCEMENT, 4935 40th Avenue Nw
Calgary, Alberta, T3A 2N1
British Columbia
DR. CHIH-HO HONG MEDICAL INC., 15300 105 Avenue
Surrey, British Columbia, V3R 6A7
Manitoba
WISEMAN DERMATOLOGY RESEARCH INC, 6 - 1170 Taylor Avenue
Winnipeg, Manitoba, R3M 3Z4
Ontario
CCA MEDICAL RESEARCH, 95 Bayly Street West
Ajax, Ontario, L1S 7K8
DERMEDGE RESEARCH INC., 333 Lakeshore Road West
Mississauga, Ontario, L5H 1G9
K. PAPP CLINICAL RESEARCH, 135 Union Street East
Waterloo, Ontario, N2J 1C4
LYNDERM RESEARCH INC, 25 Main Street Markham North
Markham, Ontario, L3P 1X2
NORTH BAY DERMATOLOGY CENTRE, 500 Cassells Street
North Bay, Ontario, P1B 3Z7
OFFICE OF DR. MICHAEL ROBERN, 1 Centrepointe Drive
Ottawa, Ontario, K2G 6E2
RESEARCH BY ICLS, 1344 Cornwall Road
Oakville, Ontario, L6J 7W5
RESEARCH TORONTO, 208 Bloor Street West
Toronto, Ontario, M5Sz 2B4
SIMCODERM MEDICAL AND SURGICAL DERMATOLOGY CENTER, 5 Quarry Ridge Road
Barrie, Ontario, L4M 7G1
SKIN CENTRE FOR DERMATOLOGY, 775 Monaghan Road
Peterborough, Ontario, K9J 5K2
WINDSOR CLINICAL RESEARCH INC, 2224 Walker Road
Windsor, Ontario, N8W 5L7
XLR8 MEDICAL RESEARCH, 2425 Tecumseh Road East
Windsor, Ontario, N8W 1E6
YORK DERMATOLOGY CENTER, 250 Harding Blvd West
Richmond Hill, Ontario, L4C 9M7
Quebec
CLINIQUE DERMATOLOGIQUE DE SAINT-JEROME, 555 Boul. Saint-antoine
