Gemcitabine and Nab-Paclitaxel vs Gemcitabine, Nab-Paclitaxel, Durvalumab and Tremelimumab as 1st Line Therapy in Metastatic Pancreatic Adenocarcinoma

Last updated:
2026-07-11
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View trial details

Overview

Official protocol title:

A RANDOMIZED PHASE II TRIAL OF GEMICITABINE AND NAB-PACLITAXEL VS GEMCITABINE, NAB-PACLITAXEL, DURVALUMAB AND TREMELIMUMAB AS 1ST LINE THERAPY IN METASTATIC PANCREATIC ADENOCARCINOMA

Intervention/treatment:
MEDI4736 (DURVALUMAB) / TREMELIMUMAB
Medical condition:
PANCREATIC ADENOCARCINOMA
Protocol code:
PA.7
Control number:
196974
Status:
Closed
Approved:
August 18, 2016
Date Completed:
Trial phase:
Phase 2
For more information:
ClinicalTrials.gov - NCT02879318
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Chris O'Callaghan
Organization
Canadian Cancer Trials Group
Phone:
6135336430
Sponsor
CANADIAN CANCER TRIALS GROUP, CANCER RESEARCH INSTITUTE, QUEEN'S UNIVERSITY

Locations

Alberta

Tom Baker Cancer Centre
Calgary, Alberta, T2N 4N2

British Columbia

BCCA - Vancouver Cancer Centre
Vancouver, British Columbia, V5Z 4E6

Manitoba

CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9

New Brunswick

The Moncton Hospital
Moncton, New Brunswick, E1C 6Z8
The Vitalite Health Network - Dr. Leon Richard
Moncton, New Brunswick, E1C 8X3

Newfoundland and Labrador

Dr. H. Bliss Murphy Cancer Centre
St. John's, Newfoundland and Labrador, A1B 3V6

Nova Scotia

QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 1V7

Ontario

Algoma District Cancer Program
Sault Ste. Marie, Ontario, P6B 0A8
Grand River Regional Cancer Centre
Kitchener, Ontario, N2G 1G3
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2
Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7
London Regional Cancer Program
London, Ontario, N6A 5W9
Niagara Health System
St. Catharines, Ontario, L2S 0A9
Odette Cancer Centre
Toronto, Ontario, M4N 3M5
Ottawa Hospital Research Institute
Ottawa, Ontario, K1H 8L6
St. Joseph's Health Centre
Toronto, Ontario, M6R 1B5
University Health Network
Toronto, Ontario, M5G 2M9

Quebec

Centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec, J1H 5N4
Centre Integre Universitaire De Sante Et De Services
Montreal, Quebec, H4J 1C5
CHUM-Centre Hospitalier de l'Universite de Montreal
Montreal, Quebec, H2X 3E4
CHUQ-Pavillon Hotel-Dieu de Quebec
Québec, Quebec, G1R 2J6
Hopital de la Cite-de-la-Sante
Laval, Quebec, H7M 3L9
L'Hotel-Dieu de Levis
Lévis, Quebec, G6V 3Z1
The Jewish General Hospital
Montreal, Quebec, H3T 1E2
The Research Institute of the McGill University
Montreal, Quebec, H4A 3J1

Saskatchewan

Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4

Results

See the results from the trial NCT02879318. This is an external link. The information is not authorized by the Government of Canada.

Date posted:
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