Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF

Last updated:
2026-07-11
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View trial details

Overview

Official protocol title:

BLINDED RANDOMIZED TRIAL OF ANTICOAGULATION TO PREVENT ISCHEMIC STROKE AND NEUROCOGNITIVE IMPAIRMENT IN ATRIAL FIBRILLATION

Intervention/treatment:
RIVAROXABAN/ ACETYLSALICYLIC ACID
Medical condition:
ATRIAL FIBRILLATION
Protocol code:
BRAIN-001
Control number:
177884
Status:
Closed
Approved:
October 16, 2014
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT02387229
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
30 Years to 62 Years
Accepts healthy volunteers: No

Contacts and locations

Contact
Sponsor
MONTREAL HEART INSTITUTE

Locations

CHU de Quebec-Universite Laval/Hotel Dieu de Quebec
Québec
Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Québec

Alberta

CardiAi Inc.
Calgary, Alberta
Libin Cardiovascular Institute of Alberta
Calgary, Alberta
University of Alberta
Edmonton, Alberta

British Columbia

North Shore Heart Center
North Vancouver, British Columbia, V5Z 1M9
Office of Dr. TunZan Maung, MD
Abbotsford British Columbia, British Columbia, V5Z 1M9
Vancouver General Hospital/UBC
Vancouver, British Columbia

Manitoba

Cardio 1
Winnipeg, Manitoba
St. Boniface Hospital
Winnipeg, Manitoba

New Brunswick

Dr. Georges-L - Dumont University Hospital Center
Moncton, New Brunswick

Nova Scotia

QEll Health Sciences Center-Halifax Infirmary
Halifax, Nova Scotia

Ontario

Cambridge Cardiac Care Center
Cambridge, Ontario
Cardiology Clinic
Kitchener, Ontario
Hamilton Health Sciences - General Site
Hamilton, Ontario
McMaster University
Hamilton, Ontario
Oakville Cardiovascular Research LP
Oakville, Ontario
One Heart Care
Mississauga, Ontario
PACE (Partners in Advanced Cardiac Evaluation)
Newmarket, Ontario
St. Mary's general Hospital
Kitchener, Ontario
St. Michael's Hospital
Toronto, Ontario
University of Ottawa Heart Institute
Ottawa, Ontario
Vizel Cardiac Research
Cambridge, Ontario
Western University - London Health Sciences Centre
London, Ontario

Quebec

CHUM
Montreal, Quebec
CISSS BSL-Hopital de Rimouski
Rimouski, Quebec
CISSS de Lanaudiere-Hopital Pierre-Le Gardeur
Terrebonne, Quebec
CISSS des Laurentides-Unite de recherche clinique
Saint-Jérôme, Quebec
CISSSMC-Hopital Charles-Lemoyne
Greenfield Park, Quebec
CIUSSS de l'Estrie-CHUS
Sherbrooke, Quebec
CIUSSS de l'Estrie-CHUS-Centre Haute-Yamaska (Hopital de Granby)
Granby, Quebec
CIUSSS du Saguenay-Lac-Saint-Jean
Chicoutimi, Quebec
CIUSSS MCQ CHAUR- Centre Hospitalier regional de Trois-Rivieres
Trois-Rivières, Quebec
Clinique Cardiologie de Levis
Lévis, Quebec
Hopital de la Cite-de-la-Sante
Laval, Quebec
Hopital du Sacre Coeur de Montreal
Montreal, Quebec
McGill University Health Center
Montreal, Quebec
Montreal Heart Institute
Montreal, Quebec, H1T1C8
Montreal Heart Institute
Montreal, Quebec
Viacar Recherche Clinique Inc.
Brossard, Quebec
Viacar Recherche Clinique Inc.
Greenfield Park, Quebec
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