Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Primary Hyperlipidemia or Mixed Dyslipidemia At Risk Of Cardiovascular Events

Last updated:
2026-08-01
Language and content disclaimer

The content and search results on this site are collected from or provided by third parties. As such some of the information may only be available in the language originally submitted by the sponsor of the trial. Learn more about the information on the search portal.

Linking to Non-Government of Canada Websites

Links to websites not under the control of the Government of Canada, including those to our social media accounts, and to clinical trial records in international registries are provided solely for the convenience of our website visitors. We are not responsible for the accuracy, currency or reliability of the content of such websites. The Government of Canada does not offer any guarantee in that regard and is not responsible for the information found through these links, nor does it endorse the sites and their content.

Visitors should also be aware that information offered by non-Government of Canada sites to which this website links is not subject to the Privacy Act or the Official Languages Act and may not be accessible to persons with disabilities. The information offered may be available only in the language(s) used by the sites in question. With respect to privacy, visitors should research the privacy policies of these non-government websites before providing personal information.

View trial details

Overview

Official protocol title:

A 52 WEEK, PHASE 3, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO ASSESS THE EFFICACY, SAFETY AND TOLERABILITY OF PF-04950615 IN SUBJECTS WITH PRIMARY HYPERLIPDEMIA OR MIXED DYSLIPIDEMIA AT RISK OF CARDIOVASCULAR EVENTS. SPIRE-LL: STUDIES OF PCSK9 INHIBITION AND THE REDUCTION OF VASCULAR EVENTS - LIPID LOWERING

Intervention/treatment:
RN316 (PF-04950615)
Medical condition:
PRIMARY HYPERLIPIDEMIA
Protocol code:
B1481045
Control number:
177847
Status:
Closed
Approved:
October 10, 2014
Date Completed:
Trial phase:
Phase 3
For more information:
ClinicalTrials.gov - NCT02100514
This is an external link. The information is not authorized by the Government of Canada.

Eligibility

Sex: ALL
Age
18 Years and older
Accepts healthy volunteers: No

Contacts and locations

Contact
Name
Pfizer ClinicalTrials.gov Call Center
Organization
Pfizer, Inc.
Phone:
1-800-718-1021
Sponsor
PFIZER CANADA INC

Locations

Alberta

LMC Clinical Research Inc. (Calgary)
Calgary, Alberta, T2H 2G4

British Columbia

Cook Street Medical Clinic
Victoria, British Columbia, V8V 4A1
Fraser Clinical Trials
New Westminster, British Columbia, V3L 3W4
Glover Medical Clinic
Langley, British Columbia, V3A 4H9
Medical Arts Health Research Group
Kamloops, British Columbia, V2C 1K7
Office of Dr. Ronald Collette MD
Burnaby, British Columbia, V5G 1T4
The Medical Arts Health Research Group
Kelowna, British Columbia, V1Y 1V6
The Medical Arts Health Research Group
Penticton, British Columbia, V2A 5C8
The Office of James K. Lai, MD Inc.
Vancouver, British Columbia, V5Z 1K3

Ontario

Aggarwal And Associates Ltd
Brampton, Ontario, L6T 0G1
Corunna Medical Research Centre
Corunna, Ontario, N0N 1G0
Kawartha Cardiology Clinical Trials
Peterborough, Ontario, K9J 0B2
LMC Clinical Research Inc. (Barrie)
Barrie, Ontario, L4M 7G1
LMC Clinical Research Inc. (Bayview)
Toronto, Ontario, M4G 3E8
LMC Clinical Research Inc. (Brampton)
Brampton, Ontario, L6S 0C9
LMC Clinical Research Inc. (Etobicoke)
Etobicoke, Ontario, M9R 4E1
LMC Clinical Research Inc. (Markham)
Markham, Ontario, L6B 0P9
LMC Clinical Research Inc. (Oakville)
Oakville, Ontario, L6M 1M1
LMC Clinical Research Inc. (Thornhill)
Thornhill, Ontario, L4J 8L7
Manna Research Inc.
Toronto, Ontario, M9W 4L6
Rouge Valley Health System - Centenary
Toronto, Ontario, M1E 4B9
Scarborough Cardiology Research
Scarborough Village, Ontario, M1E 5E9
SKDS Research Inc.
Newmarket, Ontario, L3Y 5G8
The Office of Dr. James Cha
Oshawa, Ontario, L1J 2K1

Quebec

Alpha Recherche Clinique
Québec, Quebec, G3K 2P8
C.I.C. Maurice Inc.
Trois-Rivières, Quebec, G8T 7A1
C.I.C. Mauricie Inc.
Trois-Rivières, Quebec, G8T 7A1
Centre de Depistage et de Recherche Cardiovasculaire Rive-Sud
Longueuil, Quebec, J4M2X1
Centre De Sante Et De Services Sociaux De Beauce (CSSSB)
Saint-Georges, Beauce, Quebec, G5Y 4T8
Clinique des maladies lipidiques de Quebec
Québec, Quebec, G1V 4W2
Ecogene-21
Chicoutimi, Quebec, G7H 7K9
Montreal Heart Institute
Montreal, Quebec, H1T 1C8
ViaCar Recherche Clinique Inc.
Greenfield Park, Quebec, J4V 2G8

Results

See the results from the trial NCT02100514. This is an external link. The information is not authorized by the Government of Canada.

Date posted:
Did you find what you were looking for?