This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive Bladder
Last updated:
Last updated
The date of the most recent update for each trial record in the Canadian Clinical Trial Search Portal.
2026-07-11
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A RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, PLACEBO- AND ACTIVE- CONTROLLED, MULTI-CENTER STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF COMBINATIONS OF SOLIFENACIN SUCCINATE AND MIRABEGRON COMPARED TO SOLIFENACIN SUCCINATE AND MIRABEGRON MONOTHERAPY IN THE TREATMENT OF OVERACTIVE BLADDER
Intervention/treatment:
Intervention/treatment
Name given to the drug used in the clinical trial. This may be a code name, a chemical name of the active ingredient, a non-proprietary name or brand name.
SOLIFENACIN / MIRABEGRON
Medical condition:
Medical condition
The disease or condition that's being studied in the clinical trial.
OVERACTIVE BLADDER
Protocol code:
Protocol Code
An alpha-numeric sequence generated by the sponsor that can vary in length. Used as a reference to help identify a specific clinical trial protocol. Formerly referred to as 'protocol number'.
178-CL-101
Control number:
Control number
A unique 6-digit identification number Health Canada assigns to each clinical trial application.
166448
Status:
Trial Status
The status for the clinical trial as a whole. Note that the status for each site may be different and should always be confirmed with the clinical trial sponsor. Health Canada uses information provided by the sponsor to an international clinical trial registry to determine status values for each clinical trial. Status values on the portal can include:
• Not yet recruiting - Participants are not yet being recruited or enrolled at any site. • Recruiting - Participants are currently being recruited. • Active, not recruiting - The clinical trial is ongoing but new participants are not currently being recruited or enrolled. • On hold - The clinical trial has been temporarily stopped, but it may start again. • Closed - The clinical trial has either ended normally and participants are no longer being examined or treated, or it has stopped early and will not start again. • Unknown - The status of the clinical trial has not been verified in the registry in the last 2 years. Please contact the sponsor. • No match, ongoing - Please contact sponsor for status information. • Other - Please contact sponsor for status information.
Closed
Approved:
Approved
The date that the clinical trial has been determined to meet Health Canada’s regulatory requirements. For drug clinical trials, this means that a no objection letter or an authorization was issued.
August 07, 2013
Date Completed:
Date completed
The date of the last participant’s last visit in the global study. The completion date may be actual or estimated, depending what was provided to the registry. Estimated completion dates may be in the past or future.
Trial phase:
Trial phase
The stage of a clinical trial, based on factors such as the objectives of the trial and number of participants. Phase data displayed in the portal is taken from international registry data.
For more information see "Phases of drug trials" on the Definitions webpage
This is an external link. The information is not authorized by the Government of Canada.
Eligibility
Eligibility
The characteristics people must have or the requirements they must meet to participate in the clinical trial. Eligibility criteria include both inclusion criteria (must have for a person to participate) and exclusion criteria (prevent a person from participating).
Review the exact criteria from the registry or the sponsor before making a decision to participate. The following values may be available on the portal:
Sex: an eligibility criteria based on biological characteristics. Information in the portal is based on available data and will default to 'all' when no other data is available.
Age: The age a person must be to participate in the clinical trial.
Accepts Healthy Volunteers: People who do not have the disease or condition can participate in the clinical trial.
Sex:
ALL
Age
18 Years and older
Accepts healthy volunteers:
No
Contacts and locations
Contact
Contact
Information for an individual or organisation that can respond to questions about this clinical trial. This information comes from the international registry.
The sponsor conducts the clinical trial and is responsible for every aspect. For example this could be a company, a university or an individual researcher.
ASTELLAS PHARMA EUROPE B.V.
Locations
Alberta
Site CA15029 Royal Alexandra Hospital
Edmonton, Alberta, T5H 3V9
Site CA15035 Glenrose Rehabilitation Hospital
Edmonton, Alberta, T6G 2P4
British Columbia
Site CA15033 Prohealth
Vancouver, British Columbia, V5Z 4E1
New Brunswick
Site CA15008 Private Practice
Saint John, New Brunswick, E2L 3J8
Ontario
Site CA15001 The Male/Female Health & Research Centre
Barrie, Ontario, L4M 7G1
Site CA15002 Toronto Western Hospital
Toronto, Ontario, M5T 2S8
Site CA15003 Brantford Urology Research
Brantford, Ontario, N3R 4N3
Site CA15004 Primehealth Clinical Research
Toronto, Ontario, M4S 1Y2
Site CA15006 Bramalea Medical Centre
Brampton, Ontario, L6T 4S5
Site CA15007 Eunoia2 Incorporated
Kitchener, Ontario, N2N 2B9
Site CA15013 Sunnybrook Health Sciences Center
Toronto, Ontario, M4N 3M5
Site CA15031 Centre for Applied Urology Research (CAUR)
Kingston, Ontario, K7L 3J7
Site CA15032 Stanley Flax Medical Prof Corp
North York, Ontario, M2J 1V1
Site CA15034 Oxford/Richmond Medical
London, Ontario, N6A 5R9
Site CA15042 G. Kenneth Jansz Medicine Professional Corporation